Publication
Tweaking DNA of myeloid cells curbs cancer spread
Publications associées (46)
Perivascular Macrophages Limit Permeability
Michele De Palma, Melody Swartz, Mario Leonardo Squadrito, Witold Waldemar Kilarski, Esra Güç
Objective-Perivascular cells, including pericytes, macrophages, smooth muscle cells, and other specialized cell types, like podocytes, participate in various aspects of vascular function. However, aside from the well-established roles of smooth muscle cell ...
American Heart Association2016Theoretical and Experimental Characterization of Amino-PEG-Phosphonate-Terminated Polyphosphorhydrazone Dendrimers: Influence of Size and PEG Capping on Cytotoxicity Profiles
The synthesis of new series of PPH (poly(phosphorhydrazone)) dendrimers with amino-PEG phosphonates or the corresponding amino-PEG phosphonic acids as terminal groups is presented, from generations 1-3. The size of PEG-terminated dendrimers is experimental ...
Wiley-Blackwell2015CHO Quasispecies—Implications for Manufacturing Processes
Chinese hamster ovary (CHO) cells are a source of multi-ton quantities of protein pharmaceuticals. They are, however, immortalized cells, characterized by a high degree of genetic and phenotypic diversity. As is known for any biological system, this divers ...
MDPI2013Lighting up cells with lanthanide self-assembled helicates
Lanthanide bioprobes and bioconjugates are ideal luminescent stains in view of their low propensity to photobleaching, sharp emission lines and long excited state lifetimes permitting time-resolved detection for enhanced sensitivity. We show here how the i ...
Royal Society, The2013Automated biomanipulation of single cells
Transport of individual cells or chemical payloads on a subcellular scale is an enabling tool for the study of cellular communication, cell migration, and other localized phenomena. We present a magnetically actuated robotic system for the fully automated ...
2012In Vitro Investigation of the Cellular Toxicity of Boron Nitride Nanotubes
László Forró, Arnaud Magrez, Endre Horvath, Rita Smajda, Lenke Horváth, Beat Schwaller
Nanotubes present one of the most promising opportunities in nanotechnology with a plethora of applications in nanoelectronics, mechanical engineering, as well as in biomedical technology. Due to their structure and some physical properties, boron nitride ...
American Chemical Society2011Electrokinetic and Optical Control of Bacterial Microrobots
One of the great challenges in microscale science and engineering is the independent manipulation of cells and man-made objects on the micron scale. For such work, motile microorganisms are integrated with engineered systems to construct microbiorobots (MB ...
Institute of Physics2011Effects of solidification kinetics on microstructure formation in binary Sn-Cu solder alloys
Three binary Sn-Cu solder alloys of near-eutectic composition have been directionally solidified at different growth rates. The competition between primary tetragonal Sn cells/dendrites and eutectic is interpreted with the coupled zone concept. It is also ...
Elsevier2011FcRgamma activation regulates inflammation-associated squamous carcinogenesis
Michele De Palma, Ferdinando Pucci
Chronically activated leukocytes recruited to premalignant tissues functionally contribute to cancer development; however, mechanisms underlying pro- versus anti-tumor programming of neoplastic tissues by immune cells remain obscure. Using the K14-HPV16 mo ...
2010Establishment of polarized microglial cells derived from mouse embryonic stem cells
Microglia are the resident immune cells of the central nervous system (CNS). Microglia undergo rapid activation in response to even minor pathological changes in the CNS. The activation state of microglia and tissue macrophages is characterized by two extr ...
2010