Publication

Multimodal imaging combining time-domain near-infrared optical tomography and continuous-wave fluorescence molecular tomography

Publications associées (33)

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Near-Infrared Optical Tomography with Single-Photon Avalanche Diode Image Sensors

Juan Mata Pavia

In the past decades different methods based on magnetic resonance imaging (MRI) and positron emission tomography (PET) have been developed to image a variety of hemodynamic parameters in tissue. However, simultaneous high resolution imaging of oxy- and deo ...

EPFL2015

Combined Optical Coherence and Fluorescence Microscopy to assess dynamics and specificity of pancreatic beta-cell tracers

Theo Lasser, Christophe Pache, Anne Grapin-Botton, Arno Pino Bouwens, Daniel Pawel Szlag, Corinne Berclaz, Antonio Lopez

The identification of a beta-cell tracer is a major quest in diabetes research. However, since MRI, PET and SPECT cannot resolve individual islets, optical techniques are required to assess the specificity of these tracers. We propose to combine Optical Co ...

2015

Questions such as biomolecular interactions, kinetics of enzymes, DNA conformational changes, cellular structures properties (among others) are addressed by characterizing the biological function of molecules. This function depends on their structure and t ...

EPFL2014

Fluorescence microscopy techniques are well established research tools and have proven their use in a large variety of biomedical applications. Microscopic molecular contrast is achieved by imaging fluorescent dyes that bind specifically to a molecule of i ...

EPFL2013

Optical Coherence Microscopy (OCM) is a three-dimensional imaging technique that provides cross-sectional views of the subsurface microstructure of biological tissue, with a high axial and lateral resolution. In OCM, a low time coherence light source is sp ...

EPFL2012

The Gemperline research group is currently working on a research project to characterize chemical batch reactions in slurry mixtures with light scattering properties. One of our primary goals is to determine light absorption and light scattering properties ...

2010

Extended Focus Optical Coherence Microscopy

Martin Villiger

Optical coherence tomography (OCT) is an interferometric imaging technique that can provide depth resolved cross-sectional views of biological tissue. OCT employs light with low temporal and yet high spatial coherence. The sample is illuminated point by po ...

EPFL2010

Development of Minimally-Invasive Optical Methods to Individualize the Doses Used for Therapeutic Applications of Light

Filippo Piffaretti

Despite the experience gained over several decades in various types of light-based medical treatments, the optimization of the corresponding therapeutic protocols and accurate forecasting of their outcome have not yet been achieved in many cases. The diffi ...

EPFL2010

This work includes the fabrication of plasmonic nanostructures as well as the investigation of their optical properties in the near-field and in the farfield. As expressed in the title of this thesis the focus lies in the subwavelength confinement and enha ...

EPFL2008

Extended focus optical coherence microscopy and fluorescence lifetime imaging

Theo Lasser, Rainer Leitgeb, Martin Villiger, Adrian Bachmann, Cédric Blatter

Fourier domain Optical coherence microscopy (FDOCM) offers excellent sensitivity and high axial resolution to image the structure of biological tissue. The depth information is extracted in parallel and allows very high volume acquisition rates. The presen ...

SPIE2008