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Label-free, scalable and point-of-care imaging platform for rapid analysis of biomarker

Publications associées (36)

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High sensitivity, incoherent differential imaging

Chiara Bonati

Microscopic visualisation of optically transparent samples has been a topic of interest for several decades. Features such as density or chemical composition can influence the optical phase of transmitted light, and phase contrast can reveal these structur ...

EPFL2022

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Direct visualization is often sought to elucidate flow patterns and validate models to predict the filling kinetics during processes whereby a liquid resin infiltrates a textile porous preform. Here, X-ray phase contrast interferometry is evaluated to imag ...

2021

Multi-spectral image priniting method

Martin Vetterli, Yves Bellouard, Arnaud Latty, Adam James Scholefield, Gilles Baechler, Michalina Wanda Pacholska

The present disclosure concerns a multi-spectral image printing method. The method includes the steps of: - providing a multi-spectral image; - providing a material; - determining changes in a refractive index value of the material permitting to reproduce ...

2019

Neuroimaging techniques aim at revealing the anatomy and functional organisation of cerebral structures. Over the past decades, functional magnetic resonance imaging (fMRI) has revolutionized our understanding of human cerebral physiology through its abili ...

EPFL2018

Compact lensless digital holography

Manon Rostykus

Microscopy is of high interest for biology since it allows imaging features that are too small to be seen with naked eyes. However, cells are mostly transparent to visible and infrared light which makes it difficult to see with a traditional microscope. To ...

EPFL2018

Coherent imaging from bacteria to multicellular organisms

Séverine Coquoz

Structural and functional imaging of cells, tissues and organisms is crucial for understanding biomedical processes. Fluorescence microscopy is an established tool and has contributed to many discoveries in the life sciences. This technique provides molecu ...

EPFL2017

This paper presents an extension of the spatio-spectral ("3D") image reconstruction algorithm called PAINTER (Polychromatic opticAl INTErferometric Reconstruction software). The algorithm is able to solve large scale problems and relies on an iterative pro ...

SPIE2016

Learning Approach to Optical Tomography

Michaël Unser, Demetri Psaltis, Cédric René Jean Vonesch, Ulugbek Kamilov, Alexandre Goy

Optical tomography has been widely investigated for biomedical imaging applications. In recent years optical tomography has been combined with digital holography and has been employed to produce high-quality images of phase objects such as cells. In this p ...

Optical Soc Amer2015

Acquisition of multiple phase derivatives from a single frame in digital holographic interferometry

Pramod Rastogi, Rishikesh Dilip Kulkarni

This paper proposes a technique to extract two-dimensional multiple phase derivatives (strains, slopes, and shearing strains) from a single frame of the interference fringe pattern recorded in an optical setup with multiple illumination beams. In the propo ...

Spie-Soc Photo-Optical Instrumentation Engineers2015

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We propose and experimentally demonstrate a digital holographic camera which can be attached to the camera port of a conventional microscope for obtaining digital holograms in a self-reference configuration, under short coherence illumination and in a sing ...

Optical Soc Amer2014