Publication
Mechanistic studies of DNP and applications of hyperpolarized probes to study renal physiology and metabolism
Publications associées (96)
Robust gamma-aminobutyric acid and energy metabolism measurements by proton and phosphorus magnetic resonance spectroscopy and fingerprinting
Magnetic resonance spectroscopy (MRS) is the only technique that can detect endogenous metabolites directly and non-invasively in vivo. It allows to identify different metabolites and analyze the dynamic neurochemical processes in the brain, skeletal muscl ...
EPFL2023Harmonization of multi-scanner in vivo magnetic resonance spectroscopy: ENIGMA consortium task group considerations
Magnetic resonance spectroscopy is a powerful, non-invasive, quantitative imaging technique that allows for the measurement of brain metabolites that has demonstrated utility in diagnosing and characterizing a broad range of neurological diseases. Its impa ...
FRONTIERS MEDIA SA2023Towards optical MAS magnetic resonance using optical traps
Giovanni Boero, Nergiz Sahin Solmaz, Reza Farsi, Jens Anders
Higher magic angle spinning (MAS) frequencies than currently available are desirable to improve spectral resolution in NMR and EPR systems. While conventional strategies employ pneumatic spinning limited by fluid dynamics, this paper demonstrates the devel ...
Amsterdam2023Dynamic Nuclear Polarization of Inorganic Halide Perovskites
David Lyndon Emsley, Michael Allan Hope, Dominik Józef Kubicki, Gabriele Stevanato, Aditya Mishra
NMR, EPR, XRD datasets and SEM image for the research article titled "Dynamic Nuclear Polarization of Inorganic Halide Perovskites". For further details see the readme.txt file. ...
EPFL Infoscience2023Diamond-Based Nanoscale Quantum Relaxometry for Sensing Free Radical Production in Cells
Mayeul Sylvain Chipaux, Hoda Shirzad
Diamond magnetometry makes use of fluorescent defects in diamonds to convert magnetic resonance signals into fluorescence. Because optical photons can be detected much more sensitively, this technique currently holds several sensitivity world records for r ...
WILEY-V C H VERLAG GMBH2022Dnp biosensor
Jean-Philippe Ansermet, Jonas Milani
Method for detecting a change in molecular tumbling of an electron-spin labelled system (1) in solution. Nuclear spins of the entire solution are measured in solution using Overhauser dynamic nuclear polarization in a first reference measurement, and then ...
2022H-1 Hyperpolarization of Solutions by Overhauser Dynamic Nuclear Polarization with C-13-H-1 Polarization Transfer
David Lyndon Emsley, Yu Rao, Pinelopi Moutzouri, Amrit Venkatesh
Dynamic nuclear polarization (DNP) is a method that can significantly increase the sensitivity of nuclear magnetic resonance. The only effective DNP mechanism for in situ hyperpolarization in solution is Overhauser DNP, which is inefficient for H-1 at high ...
AMER CHEMICAL SOC2022Solid-state NMR spectroscopy
Solid-state nuclear magnetic resonance (NMR) spectroscopy is an atomic-level method to determine the chemical structure, 3D structure and dynamics of solids and semi-solids. This Primer summarizes the basic principles of NMR spectroscopy as applied to the ...
SPRINGERNATURE2021Theory and simulations of homonuclear three-spin systems in rotating solids
David Lyndon Emsley, Gabriele Stevanato, Pinelopi Moutzouri, Bruno Simões de Almeida
The homonuclear dipolar coupling is the internal spin interaction that contributes the most to the line shapes in magic-angle-spinning (MAS) H-1 NMR spectra of solids, and linewidths typically extend over several hundred Hertz, limiting the H-1 resolution. ...
AIP Publishing2021HP agents and biochemical interactions
Hikari Ananda Infinity Yoshihara
The intense but transient increase in nuclear magnetic resonance signal provided by dynamic nuclear polarization (DNP) has enabled a range of new applications, including rapid, minimally-invasive metabolic imaging at the second timescale. This chapter prov ...
Academic Press2021