Self-assembly of protein-polymer conjugates for drug delivery
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Peptide based and peptide hybrid materials represent two interesting and challenging classes of biomaterials. Both classes consist of and contain, respectively, one or more polypeptide blocks, endowing the resulting polymers with enhanced self-assembly pro ...
This thesis presents the first experimental results of a scanning tunneling microscopy (STM) and scanning tunneling spectroscopy (STS) investigation of rubrene at the supramolecular, molecular and submolecular level. Based on its semiconducting and fluores ...
In this thesis, the use of nanotemplates for steering the molecular self-organization at metallic surfaces is investigated. Nanotemplates are surfaces that exhibit a periodic variation of the adhesion energy on the nanometer scale. Preferential adsorption ...
High-d. microarrays of attoliter vol. elements can be created within minutes in a parallel and effortless manner by using self-assembly of nanometer-size components based on biol. recognition. These ultrasmall vols. allow localization of single mols., scre ...
Passing from millimeter to micrometer scale, the traditional pick and place method for assembling large amount of compounds be- comes difficult and time consuming. At micrometer scale it is then very important to have other assembling methods. This work pr ...
This paper discusses the solid state and melt nanoscale structure of a series of novel poly(ethylene glycol) (PEG) hybrid di- and triblock copolymers, which contain amphiphilic β-strand peptide sequences. The block copolymers have been prepared via solid-p ...
Coverage-dependent self-assembly of rubrene molecules on different noble metal surfaces, Au(111) and Au(100), Ag(111) and Ag(100), is presented. On Au(111), the homochiral supramolecular assemblies evolve with increasing rubrene coverage from very small st ...
The outer membrane protein OmpF from Escherichia coli is a member of a large family of b-barrel membrane proteins. Some, like OmpF, are pore-forming proteins while others are active transporters or enzymes. We have previously shown that the receptor-bindin ...
The self-assembly in aqueous solution of hybrid block copolymers consisting of amphiphilic ?-strand peptide sequences flanked by one or two PEG chains was investigated by means of circular dichroism spectroscopy, small-angle X-ray scattering, and transmiss ...
This review discusses the potential of block copolymer type macromolecular building blocks for the preparation of self-assembled materials. Three different classes of block copolymer type architectures will be distinguished: i) coil-coil diblock copolymers ...
