Publication
Metabolic contrast agents produced from transported solid C-13-glucose hyperpolarized via dynamic nuclear polarization
Publications associées (35)
Variability and reproducibility of multi-echo T2 relaxometry: Insights from multi-site, multi-session and multi-subject MRI acquisitions
Jean-Philippe Thiran, Friedhelm Christoph Hummel, Tobias Kober, Tom Hilbert, Erick Jorge Canales Rodriguez, Gabriel Girard, Elda Fischi Gomez, Marco Pizzolato, Gian Franco Piredda, Thomas Yu, Takuya Morishita, Elena Beanato, Alessandro Daducci, Maximilian Jonas Wessel, Chang-Hyun Park, Philipp Johannes Koch, Andéol Geoffroy Cadic-Melchior, Julia Brügger
Quantitative magnetic resonance imaging (qMRI) can increase the specificity and sensitivity of conventional weighted MRI to underlying pathology by comparing meaningful physical or chemical parameters, measured in physical units, with normative values acqu ...
2022HP agents and biochemical interactions
Hikari Ananda Infinity Yoshihara
The intense but transient increase in nuclear magnetic resonance signal provided by dynamic nuclear polarization (DNP) has enabled a range of new applications, including rapid, minimally-invasive metabolic imaging at the second timescale. This chapter prov ...
Academic Press2021Methods to Enhance Nuclear Magnetic Resonance Sensitivity at High Magnetic Field
MR is a well-established technique routinely used in preclinical and clinical studies. This thesis focussed on the improvement of sensitivity of different methods in MR.
Hyperpolarized 129Xe gas is used for studying pulmonary disease or cerebral perfusion ...
EPFL2021Mechanistic studies of DNP and applications of hyperpolarized probes to study renal physiology and metabolism
Dissolution dynamic nuclear polarization (dDNP) is a powerful technique that enhances the magnetic resonance signal of nuclear spins by several orders of magnitude. DNP relies on the principle of cross-relaxation by electron spins driven out of equilibrium ...
EPFL2021Nanodiamond Relaxometry-Based Detection of Free-Radical Species When Produced in Chemical Reactions in Biologically Relevant Conditions
Diamond magnetometry is a quantum sensing method involving detection of magnetic resonances with nanoscale resolution. For instance, T1 relaxation measurements, inspired by equivalent concepts in magnetic resonance imaging (MRI), provide a signal that is e ...
AMER CHEMICAL SOC2020Fat navigators based retrospective motion correction strategies for brain magnetic resonance imaging
Magnetic resonance resonance (MRI) is a widely used modality to obtain in vivo tissue information.
Clinical applications are near countless, and almost all body parts can be examined using an MR
scanner. As the method is non invasive, does not use ionizing ...
EPFL2020Engineering Parallel Transmit/Receive Radio-Frequency Coil Arrays for Human Brain MRI at 7 Tesla
Magnetic resonance imaging is widely used in medical diagnosis to obtain anatomical details of the human body in a non-invasive way. Clinical MR scanners typically operate at a static magnetic field strength (B0) of 1.5T or 3T. However, going to higher fie ...
EPFL2019High-Field C-13 Dynamic Nuclear Polarization in Nanodiamond
Stefano Alberti, Jean-Philippe Ansermet, Jérémy Genoud, Serguei Sekatski, Murari Soundararajan, Dongyoung Yoon
Hyperpolarization in diamond via dynamic nuclear polarization (DNP) has attracted a lot of interest for various applications as diamond exhibits extremely long C-13 spin relaxation times and has endogenous polarizing agents in the form of crystalline defec ...
2019Development and Optimization of Methods for Accelerated Magnetic Resonance Imaging
Magnetic resonance imaging (MRI) has yielded great success as a medical imaging modality in the past decades, and its excellent soft tissue contrast is used in clinical routine to support diagnosis today. However, MRI is still facing challenges. For exampl ...
EPFL2018Non-invasive diagnosis and metabolic consequences of congenital portosystemic shunts in C57BL/6 J mice
Hongxia Lei, Ana Francisca Leal Silva Soares
This study demonstrates the suitability of magnetic resonance imaging (MRI) and magnetic resonance angiography (MRA) for the imaging of congenital portosystemic shunts (PSS) in mice, a vascular abnormality in which mesenteric blood bypasses the liver and i ...
2018