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Metabolic contrast agents produced from transported solid C-13-glucose hyperpolarized via dynamic nuclear polarization

Publications associées (35)

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Low-Cost High-Performance MRI

Najat Salameh

Magnetic Resonance Imaging (MRI) is unparalleled in its ability to visualize anatomical structure and function non-invasively with high spatial and temporal resolution. Yet to overcome the low sensitivity inherent in inductive detection of weakly polarized ...

Nature Publishing Group2015

De l'usage des protons hyperpolarisés pour augmenter la sensibilité de la RMN

Aurélien Bornet

Nuclear Magnetic Resonance (NMR) has become an inescapable technique for spectroscopic identification. Its main advantage comes from the sensitivity of NMR active nuclei embedded in a molecule to their chemical environment. NMR is also used daily in medica ...

EPFL2015

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Conventional magnetic resonance imaging (MRI) measures of multiple sclerosis patients provide limited information about the nature and the extent of brain damage and repair. We established a clinically compatible protocol including quantitative MRI techniq ...

2014

Ultra-High Field Birdcage Coils: a Comparison Study at 14.1T

Rolf Gruetter, Hongxia Lei, Tian Cheng, Arnaud Comment

An essential feature of magnetic resonance (MR) probes for magnetic resonance imaging and spectroscopy is the ability to generate uniform B-1(+) excitation in a volume of interest. When the magnetic field strength is increased, leading to an increase in re ...

Ieee2014

Methods for Molecular Magnetic Resonance Imaging and Magnetic Resonance Spectroscopy using Hyperpolarized Nuclei

Riccardo Balzan

Since the introduction 10 years ago of the dissolution method, Dynamic Nuclear Polarization (DNP) became a widely applied and powerful technique to enhance nuclear magnetic resonance (NMR) signals of low naturally abundant, insensitive nuclear spins for an ...

EPFL2013

Decoupling of Magnetic Resonance Signals in Time and Frequency Domain

Nuclear magnetic resonance (NMR) was discovered in the first half of the 20th century. Today, neither analytical chemistry without NMR spectroscopy nor medical diagnostics without magnetic resonance imaging (MRI) could be imagined. A magnetic resonance sig ...

EPFL2013

Spread spectrum magnetic resonance imaging

Jean-Philippe Thiran, Rolf Gruetter, Pierre Vandergheynst, Dimitri Nestor Alice Van De Ville, Yves Wiaux, José Pedro Rebelo Ferreira Marques, Gilles Puy

We propose a novel compressed sensing technique to accelerate the magnetic resonance imaging (MRI) acquisition process. The method, coined spread spectrum MRI or simply s2MRI, consists of pre-modulating the signal of interest by a linear chirp before rando ...

Institute of Electrical and Electronics Engineers2012

Effects of MRI scan acceleration on brain volume measurement consistency

Cristina Granziera

To evaluate the effects of recent advances in magnetic resonance imaging (MRI) radiofrequency (RF) coil and parallel imaging technology on brain volume measurement consistency. ...

Wiley-Blackwell2012

A pipeline approach with spatial information for segmenting multiple sclerosis lesions on brain magnetic resonance imaging

Meritxell Bach Cuadra, Mariano Cabezas Grebol

Conventional magnetic resonance imaging (MRI) techniques are highly sensitive to detect multiple sclerosis (MS) plaques, enabling a quantitative assessment of inﬂammatory activity and lesion load. In quantitative analysis of focal lesions, manual or semi-a ...

2011

A major challenge in cancer biology is to monitor and understand cancer metabolism in vivo with the goal of improved diagnosis and perhaps therapy. Because of the complexity of biochemical pathways, tracer methods are required for detecting specific enzyme ...

2011