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Bundle-Specific Axon Diameter Index as a New Contrast to Differentiate White Matter Tracts

Publications associées (62)

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Assessing feasibility and reproducibility of a bundle-specific framework on in vivo axon diameter estimates at 300mT/m

Jean-Philippe Thiran, Gabriel Girard, David Paul Roger Romascano, Jonathan Rafael Patino Lopez, Alessandro Daducci, Muhamed Barakovic, Maxime Descoteaux, Giorgio Innocenti

In vivo quantitative estimation of axon diameter in the white matter could bring new tools to study the structural and functional architecture of the brain. Recently, the feasibility of axon diameter estimation with diffusion-weighted MRI (DW-MRI) has been ...

2018

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Many closed-form analytical models have been proposed to relate the diffusion-weighted magnetic resonance imaging (DW-MRI) signal to microstructural features of white matter tissues. These models generally make assumptions about the tissue and the diffusio ...

2018

Intra- and extra-axonal axial diffusivities in the white matter: Which one is faster?

Ileana Ozana Jelescu, Nicolas Kunz

A two-compartment model of diffusion in white matter, which accounts for intra- and extra-axonal spaces, is associated with two plausible mathematical scenarios: either the intra-axonal axial diffusivity Da,‖ is higher than the extra-axonal De,‖ (Branch 1) ...

2018

Fiber orientation distribution function from non-negative sparse recovery with quantitative analysis of local fiber orientations and tractography using DW-MRI datasets

Gabriel Girard

Diffusion weighted MRI (DW-MRI) is the unique non-invasive imaging modality capable of estimating in vivo the structure of the white matter. In this paper, we propose, evaluate and validate a new DW-MRI method to model and recover high quality tractogram e ...

2018

AxTract: Toward microstructure informed tractography

Jean-Philippe Thiran, Gabriel Girard, Alessandro Daducci, Maxime Descoteaux

Diffusion-weighted (DW) magnetic resonance imaging (MRI) tractography has become the tool of choice to probe the human brain's white matter in vivo. However, tractography algorithms produce a large number of erroneous streamlines (false positives), largely ...

Wiley-Blackwell2017

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The development of more effective approaches for controlling dexterous hand prostheses is an important area of research currently addressed by several groups with the aim of improving the quality of life of amputees. It is particularly important to establi ...

Springer International Publishing Ag2017

The corpus callosum establishes the anatomical continuity between the 2 hemispheres and coordinates their activity. Using histological tracing, single axon reconstructions, and diffusion tractography, we describe a callosal projection to n caudatus and put ...

Oxford University Press2017

Neuroprosthetic systems are designed to interface with the nervous system, for the replacement or restoration of damaged functions in the motor and/or sensory systems. In order to have an efficient communication with the nervous tissue leading to optimized ...

EPFL2017

We investigate the theory of principal bundles from a homotopical point of view. In the first part of the thesis, we prove a classification of principal bundles over a fixed base space, dual to the well-known classification of bundles with a fixed structur ...

EPFL2017

In-vivo Bundle-Specific Axon Diameter Distributions Estimation across the Corpus Callosum

Jean-Philippe Thiran, Gabriel Girard, David Paul Roger Romascano, Alessandro Daducci, Muhamed Barakovic, Maxime Descoteaux

Over the last decade microstructure imaging has become commonly endorsed to estimate quantitative features of neuronal tissue. However, those techniques estimate the microstructure only locally. Microstructure informed tractography was recently proposed to ...

2017