Nanomechanical bio-sensing for fast and reliable detection of viability and susceptibility of microorganisms
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Pathogens of bacterial and viral origin hijack pathways operating in eukaryotic cells in many ways in order to gain access into the host, to establish themselves and to eventually produce their progeny. The detailed molecular characterization of the subver ...
Inkjet printing of functional materials, photolithography and micromolding are 3 different techniques largely used in the field of micro-electromechanical systems (MEMS) with increasing interest for the fabrication of new devices and the development of new ...
The shape and dimensions of an atomic force microscope tip are crucial factors to obtain high resolution images at the nanoscale. When measuring samples with narrow trenches, inclined sidewalls near 90 or nanoscaled structures, standard silicon atomic forc ...
The era of scanning probe microscopy (SPM) started twenty years ago. A cut gold cantilever with a glued diamond stylus served as the scanning probe. Within a few years the crystalline silicon (Si) became the – up to today – predominant SPM probe material. ...
Compartmentalization is a defining feature of eukaryotic cells that allows the spatial segregation of different functions, such as protein and lipid synthesis, and ensures their fidelity and efficiency. This imposes the need for an intense flux of metaboli ...
Living organisms are endowed with three structural principles: multicellular architecture, cellular division, and cellular differentiation. Implemented in digital according to these principles, our bit slice processors present self-organizing mechanisms li ...
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We present a parallel, full wafer technique for deposition of catalyst on released scanning probe bodies for the growth of individual high aspect-ratio Si nanowire tips. 1-D probes are necessary for imaging high aspect-ratio nano-patterns, such as deep and ...
Microdevices dedicated to monitor metabolite levels have recently enabled many applications in the field of cell analysis, to monitor cell growth and development of numerous cell lines. By combining the traditional technology used for electrochemical biose ...
This thesis looks at surface-bound nanowires and nanoparticles, the mechanical and the metrological properties of which are of practical importance in the realization of nanometer-scale electronics. Atomic force microscope (AFM) was the main instrument of ...
Atomic Force Microscopy (AFM) techniques are used with one- or two-dimensional arrays of piezoresistive probes for parallel imaging. We present a newly designed AFM platform to drive these passivated piezoresistive cantilever arrays in air and liquid envir ...