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High-resolution fast-tomography brain-imaging beamline at the Taiwan Photon Source

Publications associées (32)

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Time-resolved Single-photon Detector Arrays for High Resolution Near-infrared Optical Tomography

Scott Anthony Lindner

Oxygenation is an important marker in many clinical settings, e.g. diagnosing ischaemic brain injuries in preterm infants or determining treatment effectiveness in cancer patients. Despite significant efforts to determine the oxygenation state of the human ...

EPFL2018

In hemiparetic stroke, functional recovery of paretic limb may occur with the reorganization of neural networks in the brain. Neuroimaging techniques, such as magnetic resonance imaging (MRI), have a high spatial resolution which can be used to reveal anat ...

2018

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Amyloid beta accumulation into insoluble plaques (A beta p) is known to play a significant role in the pathological process in Alzheimer's disease (AD). The presence of A beta p is also one of the neuropathological hallmarks for the disease. AD final diagn ...

International Union of Crystallography (IUCr)2016

We present in this study results from X-ray tomographic microscopy with synchrotron radiation performed both in attenuation and phase contrast modes on a limestone sample during two stages of water drying. No contrast agent was used in order to increase th ...

Wiley-Blackwell2015

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A 3D phase-field (PhF) model has been developed to study the formation of micropores constrained to grow within a well-developed solid network. The model accounts for the equilibrium condition at triple (solid-liquid-pore) lines and the partitioning of dis ...

Springer Verlag2015

Characterization of structural disturbances in peats by X-ray CT-based density determinations

Alexandre Buttler, Pascal Turberg, Fränz Zeimetz

Bulk densitywas determined indirectly in peat samples by X-ray computed tomography (X-ray CT) and compared with density values obtained by standard laboratory methods. Five Histosols were collected in the same cut-over peatland, representing various degree ...

Wiley-Blackwell2014

Feasibility of direct mapping of cerebral fluorodeoxy-D-glucose metabolism in situ at subcellular resolution using soft X-ray fluorescence

Rolf Gruetter, Mario Gaetano Lepore, Carole Poitry-Yamate, Vincent Gajdosik

Glucose metabolism is difficult to image with cellular resolution in mammalian brain tissue, particularly with (18) fluorodeoxy-D-glucose (FDG) positron emission tomography (PET). To this end, we explored the potential of synchrotron-based low-energy X-ray ...

Wiley-Blackwell2013

A sensitive x-ray phase contrast technique for rapid imaging using a single phase grid analyzer

Peter Modregger, Simon Rutishauser, Christian David, Marco Stampanoni

Phase contrast x-ray imaging (PCXI) is a promising imaging modality, capable of sensitively differentiating soft tissue structures at high spatial resolution. However, high sensitivity often comes at the cost of a long exposure time or multiple exposures p ...

Optical Society of America2013

Direct mapping of 19F in 19FDG-6P in brain tissue at subcellular resolution using soft X-ray fluorescence

Rolf Gruetter, Carole Poitry-Yamate

Low energy x-ray fluorescence (LEXRF) detection was optimized for imaging cerebral glucose metabolism by mapping the fluorine LEXRF signal of 19 F in 19 FDG, trapped as intracellular 19 F-deoxyglucose-6-phosphate ( 19 FDG-6P) at 1μm spatial resolution from ...

2013

Full-field X-ray microscopy is a valuable tool for 3D observation of biological systems. In the soft X-ray domain organelles can be visualized in individual cells while hard X-ray microscopes excel in imaging of larger complex biological tissue. The field ...

2012