A new paradigm for leprosy diagnosis based on host gene expression
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Vacuum-bag processing of honeycomb sandwich structures faces particular challenges compared to autoclave sandwich fabrication for aeronautics, a consequence of using, at the most, atmospheric pressure for their manufacturing. In particular, the adhesion of ...
We present a full field laser Doppler imaging instrument that enables real-time in vivo assessment of blood flow in dermal tissue and skin. The instrument monitors the blood perfusion in an area of about 50cm2 with 480 x 480 pixels per frame at a rate of 1 ...
Altered serine protease activity is associated with skin disorders in humans and in mice. The serine protease channel-activating protease-1 (CAP1; also termed protease serine S1 family member 8 (Prss8)) is important for epidermal homeostasis and is thus in ...
2011
Pathogenetic processes that facilitate the entry, replication, and persistence of Mycobacterium tuberculosis (MTB) in the mammalian host likely include the regulated expression of specific sets of genes at different stages of infection. Identification of g ...
2003
In non-autoclave processing of sandwich structures, the pressure level inside the honeycomb becomes a critical process parameter, which depends on the permeability to air of the upper skin. In this work, prepreg and adhesive permeabilities were determined ...
Elsevier2010
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Engineering of fetal tissue has a high potential for the treatment of acute and chronic wounds of the skin in humans as these cells have high expansion capacity under simple culture conditions and one organ donation can produce Master Cell Banks which can ...
This project investigates skin anatomy and physiology by three optical, non-invasive techniques: Fringe projection topography mainly for the investigation of tissue topography Parallel laser Doppler blood flow imaging for the investigation of tissue micro ...
The twin arginine translocation (Tat) system is used by many bacteria to export fully folded proteins containing cofactors. Here, we show genetically that this system is essential for Mycobacterium tuberculosis, as the tatAC operon and tatB genes could be ...
Leprosy, a chronic human disease with potentially debilitating neurological consequences, results from infection with Mycobacterium leprae. This unculturable pathogen has undergone extensive reductive evolution, with half of its genome now occupied by pseu ...
Mycobacterium tuberculosis, the causative agent of tuberculosis, possesses a class Ib ribonucleotide reductase (RNR), encoded by the nrdE and nrdF2 genes, in addition to a putative class II RNR, encoded by nrdZ. In this study we probed the relative contrib ...
