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Revealing the complexity of ultra-soft hydrogel re-swelling inside the brain

Publications associées (44)

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Integration of hybrid material systems in conformable neural interfaces

Florian Dylan Fallegger

Neural interfaces are devices that are implanted into the body and interface electrically with the central (CNS) or peripheral nervous system. They are inserted surgically for short periods of time or chronically to diagnose or treat several neural disease ...

EPFL2020

Multi T1-weighted contrast MRI with fluid and white matter suppression at 1.5 T

Tobias Kober, Giulio Gambarota

Introduction: The fluid and white matter suppression sequence (FLAWS) provides two T1-weighted co-registered datasets: a white matter (WM) suppressed contrast (FLAWS1) and a cerebrospinal fluid (CSF) suppressed contrast (FLAWS2). FLAWS has the potential to ...

ELSEVIER SCIENCE INC2019

Soft microfabricated neural implants: a path towards translational implementation

Nicolas Vachicouras

Neuroprosthetics are a class of medical devices that aim to restore lost or impaired functions of the nervous system by electrical stimulation or recording of neural tissue. State of the art neural implants suffer today from a mechanical mismatch compared ...

EPFL2019

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Computational models are powerful tools for exploring the properties of complex biological systems. In neuroscience, data-driven models of neural circuits that span multiple scales are increasingly being used to understand brain function in health and dise ...

CELL PRESS2019

Creatine (Cr) is an important organic compound acting as intracellular high-energy phosphate shuttle and in energy storage. While located in most cells where it plays its main roles in energy metabolism and cytoprotection, Cr is highly concentrated in musc ...

Elsevier2017

Brain-controlled neuroprosthetic interventions to restore locomotion after contusion spinal cord injury in the rat

Marco Bonizzato

Spinal cord injury (SCI), second only to stroke, is the leading cause of paralysis. Therapies based on electrical stimulation of the spinal cord and other locomotor areas of the Nervous System improve motor control in people with neurotrauma. Neuromodulati ...

EPFL2017

In-situ photopolymerized and monitored implants: successful application to an intervertebral disc replacement

Dominique Pioletti, Christophe Moser, Andreas Schmocker, Azadeh Khoushabi

Photopolymerization is a common method to harden materials initially in a liquid state. A surgeon can directly trigger the solidification of a dental implant or a bone or tissue filler by using ultra-violet light. Traditionally, photopolymerization has bee ...

Spie-Int Soc Optical Engineering2016

A library of polymer-coated gold nanoparticles (AuNPs) differing in size and surface modifications was examined for uptake and induction of cellular stress responses in the endoplasmic reticulum (ER stress) in human brain endothelial cells (hCMEC/D3). ER s ...

Informa Healthcare2016

Inside the human brain there are 86 Billion neurons exchanging electrical impulses to allow reaction, homoeostasis and intelligence. Their coarse organization has been described, leaving us with a fair understanding of macrocircuitry. The microcircuitry of ...

EPFL2015

Over the last decades new technologies have shed the light on an improved understanding of brain structure and function. Recently, an imaging modality referred to as diffusion Magnetic Resonance Imaging (dMRI) has emerged. By exploiting the natural motion ...

EPFL2015