Prediction of post-stroke motor recovery benefits from measures of sub-acute widespread network damages
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The motor learning process entails plastic changes in the brain, especially in brain network reconfigurations. In the current study, we sought to characterize motor learning by determining changes in the coupling behaviour between the brain functional and ...
The spinal cord is an elongated nervous structure that together with the brain forms the central nervous system. It relays sensory and motor information between the brain and the body, thus controlling most somatic and autonomic body functions. In recent y ...
"Ensure healthy lives and promote well-being for all at all ages" is the third sustainable development goal for the United Nations Agenda of 2030. This doctoral thesis fully embodied this objective by targeting stroke, a leading cause of death and disabili ...
The present relates to a method for generating a graph representing a virtually lesioned connectome of a patient after a stroke comprising:- providing structural data of the brain of the patient after the stroke;- segmenting said structural data to delinea ...
Following traumatic brain injury (TBI), cerebral metabolic dysfunction, characterized by an elevated cerebral microdialysis (CMD) lactate/pyruvate (LP) ratio, is associated with poor outcome. However, the exact pathophysiological mechanisms underlying this ...
decrement have been proposed, such as weakened acquisition of the motor skill. While the processes at play during the initial acquisition phase have been well-characterized in young adults, they were only scarcely investigated in older adults. The goal of ...
The acquisition and re-acquisition of motor skills is an important aspect of daily life and in the recovery after a stroke. Non-invasive brain stimulation (NIBS) is a technique that is used to improve motor learning and enhance motor recovery in stroke sur ...
Stroke is a disease that causes the death of precious brain cells that will never grow back and which will affect one in four humans at some point in their life. While therapies and treatments for this debilitating condition are fairly standard, their outc ...
EPFL2022
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Communication between cortical areas contributes importantly to sensory perception and cognition. On the millisecond time scale, information is signaled from one brain area to another by action potentials propagating across long-range axonal arborizations. ...
FRONTIERS MEDIA SA2022
Motivated by the need for a better understanding of post-stroke recovery and new biomarkers to improve stroke patient stratification and outcomes, this thesis investigated structure-function coupling and its role in post-stroke recovery. Furthermore, in or ...