Discontinuous Galerkin methods for Fisher-Kolmogorov equation with application to a-synuclein spreading in Parkinson's disease
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A numerical model is presented for the simulation of complex fluid flows with free surfaces. The unknowns are the velocity and pressure fields in the liquid region, together with a function defining the volume fraction of liquid. Although the mathematical ...
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Mice devoid of functional PrP genes (Prn-p(0/0) mice) showed normal development and behaviour. When inoculated with mouse scrapie prions they remained free of scrapie symptoms for at least 18 months whereas wild-type controls all died within 6 months. No p ...
Recent EPR-measurements on the mouse prion protein (mPrP) have indicated that the structured C-terminal domain is capable of binding Cu(II) with high affinity. The structure of Cu(II) binding sites in PrPc are unravelled by exploiting mixed quantum-classic ...
