Fluorogenic polymethine dyes by intramolecular cyclization
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Membrane transporters influence biological functions in the ocular lens. Here, we investigate the monocarboxylate transporter 12 (MCT12), also called creatine transporter 2 (CRT2), which is found in the ocular lens and is involved in cataract. As the age-r ...
Oxford Univ Press2017
Fluorescent probes are very important in basic research and in medicine, because of their sensitivity, versatility and quantitative capabilities. They allow the imaging of tissues or cellular compartments and the monitoring of biological events in vivo. An ...
Membrane proteins are vital to life and major therapeutic targets. Yet, understanding how they function is limited by a lack of structural information. In biological cells, membrane proteins reside in lipidic membranes and typically experience different bu ...
Tetrachloroethene (PCE) pollution threatens nature and human health due to its toxic and carcinogenic potential. Due to industrial activities, large amounts of PCE were discharged into the environment over the last decades and represent one of major ground ...
The physical and chemical characterization of biological membranes is of fundamental importance for understanding the functional role of lipid bilayers in shaping cells and organelles, steering vesicle trafficking and promoting membrane-protein signaling. ...
For targeted cellular therapy using both synthetic and natural biomaterials, there is a need for better understanding of cell penetration mechanisms. Recently, nanoparticles (NPs) coated with mixed-ligand self-assembled monolayers exhibiting order in their ...
Lateral diffusion enables efficient interactions between membrane proteins leading to signal transmission across the plasma membrane. An open question is how the spatio-temporal distribution of cell surface receptors influences the transmembrane signaling ...
American Society for Biochemistry and Molecular Biology2015
An osmotic power generator comprising an active membrane supported in a housing, at least a first chamber portion disposed on a first side of the active membrane for receiving a first electrolyte liquid and a second chamber portion disposed on a second sid ...
We present a model and its experimental validation for the optimization of the in-plane displacement of a rigid platform mounted on a compact dielectric elastomer actuator. Unlike the situation in which the mechanical prestretch of the membrane is maintain ...
We present a theoretical model to optimise the unidirectional motion of a rigid object bonded to a miniaturized dielectric elastomer actuator (DEA), a configuration found for example in AMI’s haptic feedback devices, or in our tuneable RF phase shifter. Re ...