Publication
A comprehensive stroke risk assessment by combining atrial computational fluid dynamics simulations and functional patient data
Publications associées (34)
The role of computational methods in cardiovascular medicine: a narrative review
Alfio Quarteroni, Luca Dede', Christian Vergara, Stefano Pagani
Background and Objective: Computational models of the cardiovascular system allow for a detailed and quantitative investigation of both physiological and pathological conditions, thanks to their ability to combine clinical-possibly patient-specific-data wi ...
Ame Publishing Company2024A comprehensive mathematical model for cardiac perfusion
Alfio Quarteroni, Francesco Regazzoni, Christian Vergara
The aim of this paper is to introduce a new mathematical model that simulates myocardial blood perfusion that accounts for multiscale and multiphysics features. Our model incorporates cardiac electrophysiology, active and passive mechanics, hemodynamics, v ...
Berlin2023Impact of atrial fibrillation on left atrium haemodynamics: A computational fluid dynamics study
We analyse the haemodynamics of the left atrium, highlighting differences between healthy individuals and patients affected by atrial fibrillation. The computational study is based on patient-specific geometries of the left atria to simulate blood flow dyn ...
PERGAMON-ELSEVIER SCIENCE LTD2022Association of Heart Rate Variability With Silent Brain Infarcts in Patients With Atrial Fibrillation
Jean-Marc Vesin, Vincent Schlageter
Purpose: Silent brain infarcts (SBI) are frequently detected in patients with atrial fibrillation (AF), but it is unknown whether SBI are linked to autonomic dysfunction. We aimed to explore the association of autonomic dysfunction with SBI in AF patients. ...
FRONTIERS MEDIA SA2021Predictive models for response to non-invasive brain stimulation in stroke: A critical review of opportunities and pitfalls
Friedhelm Christoph Hummel, Maximilian Jonas Wessel, Philip Egger
Background: Noninvasive brain stimulation has been successfully applied to improve stroke impairments in different behavioral domains. Yet, clinical translation is limited by heterogenous comes within and across studies. It has been proposed to develop and ...
ELSEVIER SCIENCE INC2021Clinical value of assessing motor performance in postacute stroke patients
Kamiar Aminian, Anisoara Ionescu, Fabien Massé
Background Rehabilitative treatment plans after stroke are based on clinical examinations of functional capacity and patient-reported outcomes. Objective information about daily life performance is usually not available, but it may improve therapy personal ...
BMC2021In vivo application and validation of a novel noninvasive method to estimate the end-systolic elastance
Nikolaos Stergiopoulos, Georgios Rovas, Vasiliki Bikia, Stamatia Zoi Pagoulatou
Accurate assessment of the left ventricular (LV) systolic function is indispensable in the clinic. However, estimation of a precise index of cardiac contractility, i.e., the end-systolic elastance (E-es), is invasive and cannot be established as clinical r ...
2021Metabolic fingerprints discriminating severity of acute ischemia using in vivo high-field H-1 magnetic resonance spectroscopy
Hongxia Lei, Lara Buscemi Estefanell
Despite the improving imaging techniques, it remains challenging to produce magnetic resonance (MR) imaging fingerprints depicting severity of acute ischemia. The aim of this study was to evaluate the potential of the overall high-field H-1 MR Spectroscopy ...
2020Heart Rate Variability Triangular Index as a Predictor of Cardiovascular Mortality in Patients With Atrial Fibrillation
Jean-Marc Vesin, Vincent Schlageter
Background Impaired heart rate variability (HRV) is associated with increased mortality in sinus rhythm. However, HRV has not been systematically assessed in patients with atrial fibrillation (AF). We hypothesized that parameters of HRV may be predictive o ...
WILEY2020A Proof of Concept for Computational Fluid Dynamic Analysis of the Left Atrium in Atrial Fibrillation on a Patient-Specific Basis
Alfio Quarteroni, Davide Forti, Filippo Menghini
Atrial fibrillation (AF) is associated with a fivefold increase in the risk of cerebrovascular events, being responsible of 15-18% of all strokes. The morphological and functional remodeling of the left atrium (LA) caused by AF favors blood stasis and, con ...
ASME2020