Orchestrating chromosome conformation capture analysis with Bioconductor
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This report presents challenges, opportunities, and directions for computational science and engineering (CSE) research and education for the next decade. Over the past two decades the field of CSE has penetrated both basic and applied research in academia ...
The near-exponential expansion in computing resources over the last few decades has enabled a rapid increase in the capabilities of computational science, including applications to materials research. In order to harness the available resources and acceler ...
Important progress in computational sciences has been made possible recently thanks to the increasing computing power of high performance systems. Following this trend, larger scientific studies, like brain tissue simulations, will continue to grow in the ...
Springer International Publishing2018
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Pore volume is one of the main properties for the characterization of microporous crystals. It is experimentally measurable, and it can also be obtained from the refined unit cell by a number of computational techniques. In this work, we assess the accurac ...
American Chemical Society2017
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A method to extract patterns of activity from time series of data structured as a network of objects, the method comprising the steps of creating a base graph of similar or related items from a given corpus by comparing intrinsic features of the items, com ...
2017
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Motivation: Single-cell RNA-sequencing (scRNA-seq) allows whole transcriptome profiling of thousands of individual cells, enabling the molecular exploration of tissues at the cellular level. Such analytical capacity is of great interest to many research gr ...
Oxford University Press2017
Computational methods are crucial for the analysis of diffusion magnetic resonance imaging (MRI) of the brain. Computational diffusion MRI can provide rich information at many size scales, including local microstructure measures such as diffusion anisotrop ...
2019
In modern-data analysis applications, the abundance of data makes extracting meaningful information from it challenging, in terms of computation, storage, and interpretability. In this setting, exploiting sparsity in data has been essential to the developm ...
The Center for Predictive Integrated Structural Materials Science (PRISMS Center) is creating a unique framework for accelerated predictive materials science and rapid insertion of the latest scientific knowledge into next-generation ICME tools. There are ...
BackgroundChromatin folding gives rise to structural elements among which are clusters of densely interacting DNA regions termed topologically associating domains (TADs). TADs have been characterized across multiple species, tissue types, and differentiati ...