The autism susceptibility kinase, TAOK2, phosphorylates eEF2 and modulates translation
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Cell-free biology is increasingly utilized for engineering biological systems, incorporating novel functionality, and circumventing many of the complications associated with cells. The central dogma describes the information flow in biology consisting of t ...
Oscillator system (1) comprising:- a substantially planar frame (3);- a first sub-oscillator (5), a second sub-oscillator (7), a third sub-oscillator (9), and a fourth sub-oscillator (11), each sub-oscillator (5, 7, 9, 11) comprising a substantially rigid ...
Parental Training is a methodology where therapists teach caregivers how to train their kids in specific behaviors practicing. It can be used in verbal behavior acquisition for children with autism mediated by the parents. In this paper, we are presenting ...
Copy number variants (CNVs) are major contributors to genomic imbalance disorders. Phenotyping of 137 unrelated deletion and reciprocal duplication carriers of the distal 16p11.2 220 kb BP2-BP3 interval showed that these rearrangements are associated with ...
The Notch signaling pathway is a key regulator of cell fate decisions in embryonic development and in adult tissue homeostasis. Mounting evidence suggests that Notch signaling is frequently deregulated in human neoplasms, where depending upon the cellular ...
The PIN domain plays a central role in cellular RNA biology and is involved in processes as diverse as rRNA maturation, mRNA decay and telomerase function. Here, we solve the crystal structure of the Rae1 (YacP) protein of Bacillus subtilis, a founding mem ...
In this study, the fission yeast Schizosaccharomyces pombe was used as a model system to study the cellular signaling that underlies cell cycle progression. Phosphorylation plays an important part in the regulation of this process. Kinases catalyze the tra ...
Following recent evidence for a link between interoception, emotion and empathy, we investigated relationships between these factors in autism spectrum disorder (ASD). 26 adults with ASD and 26 healthy participants completed tasks measuring interoception, ...
Re-descriptions: Aldo Rossi’s Architectural Composition. Chair of Architecture and the Public Building, Friday 1 December 2017, Room U 10:45 – 12:30. On the event of the publication in the new issue of OverHolland of the English translation of Ezio Bonfant ...
The invention relates to a radiography appliance comprising a column and a movable arm mounted such that it slides along the column and rotates about an axis oriented perpendicularly to the main direction of the column, one end of the arm comprising a dete ...
