PET REBINNING WITH REGULARIZED DENSITY SPLINES

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n-photon blockade with an n-photon parametric drive

Fabrizio Minganti, Wei Qin

We propose a mechanism to engineer an n-photon blockade in a nonlinear cavity with an n-photon parametric drive lambda(adagger n + an). When an n-photon-excitation resonance condition is satisfied, the presence of n photons in the cavity suppress ...

AMER PHYSICAL SOC2021

Roadmap toward the 10 ps time-of-flight PET challenge

Edoardo Charbon, Mathieu Benoit, Christian Morel, Joao Varela

Since the seventies, positron emission tomography (PET) has become an invaluable medical molecular imaging modality with an unprecedented sensitivity at the picomolar level, especially for cancer diagnosis and the monitoring of its response to therapy. Mor ...

IOP PUBLISHING LTD2020

Model-informed machine learning for multi-component T2 relaxometry

Jean-Philippe Thiran, Meritxell Bach Cuadra, Tobias Kober, Tom Hilbert, Erick Jorge Canales Rodriguez, Elda Fischi Gomez, Gian Franco Piredda, Thomas Yu, Cristina Granziera, Muhamed Barakovic

Recovering the distribution from multi-echo magnetic resonance (MR) signals is challenging but has high potential as it provides biomarkers characterizing the tissue micro-structure, such as the myelin water fraction (MWF). In this work, we propose to comb ...

2020

Methods and apparatus for tomographic additive manufacturing with a spatially coherent light source

Christophe Moser, Paul Delrot, Damien Claude-Marie Loterie

A method of fabricating a three-dimensional article comprises providing a spatially coherent light source (101, 201), generating from said light source (101, 201), patterns of light based on computed tomographic projections of said three-dimensional articl ...

2020

Toward Bright and Pure Single Photon Emitters at 300 K Based on GaN Quantum Dots on Silicon

Nicolas Grandjean, Raphaël Butté, Johann Nicolaï Stachurski, Gordon Jens Callsen, Sebastian Pascal Tamariz Kaufmann, Kanako Shojiki

Quantum dots (QDs) based on III-nitride semi-conductors are promising for single photon emission at noncryogenic temperatures due to their large exciton binding energies. Here, we demonstrate GaN QD single photon emitters operating at 300 K with g((2)) (0) ...

AMER CHEMICAL SOC2020

Quanta burst photography

Edoardo Charbon, Claudio Bruschini, Arin Can Ülkü, Mohit Gupta, Shantanu Gupta

Single-photon avalanche diodes (SPADs) are an emerging sensor technology capable of detecting individual incident photons, and capturing their time-of-arrival with high timing precision. While these sensors were limited to singlepixel or low-resolution dev ...

2020

Neural network training for cross-protocol radiomic feature standardization in computed tomography

Adrien Raphaël Depeursinge

Radiomics has shown promising results in several medical studies, yet it suffers from a limited discrimination and informative capability as well as a high variation and correlation with the tomographic scanner types, pixel spacing, acquisition protocol, a ...

SPIE-SOC PHOTO-OPTICAL INSTRUMENTATION ENGINEERS2019

Simultaneous Quantitation of Cationic and Non-ionic Contrast Agents in Articular Cartilage Using Synchrotron MicroCT Imaging

Goran Lovric

Early diagnosis of acute cartilage injuries enables monitoring of disease progression and improved treatment option planning to prevent post-traumatic osteoarthritis. In contrast-enhanced computed tomography (CECT), the changes in cationic agent diffusion ...

Nature Research2019

Fast model-based T-2 mapping using SAR-reduced simultaneous multislice excitation

Jean-Philippe Thiran, Tobias Kober, Tom Hilbert, José Pedro Rebelo Ferreira Marques, Gunnar Krüger

Purpose To obtain whole-brain high-resolution T-2 maps in 2 minutes by combining simultaneous multislice excitation and low-power PINS (power independent of number of slices) refocusing pulses with undersampling and a model-based reconstruction. Methods A ...

WILEY2019

Single-photon avalanche diode imagers in biophotonics: review and outlook

Edoardo Charbon, Claudio Bruschini, Ivan Michel Antolovic, Samuel Burri, Harald Arjan Robert Homulle

Single-photon avalanche diode (SPAD) arrays are solid-state detectors that offer imaging capabilities at the level of individual photons, with unparalleled photon counting and time-resolved performance. This fascinating technology has progressed at a very ...

2019

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Simultaneous Quantitation of Cationic and Non-ionic Contrast Agents in Articular Cartilage Using Synchrotron MicroCT Imaging

Goran Lovric

Nature Research2019

Single-photon avalanche diode imagers in biophotonics: review and outlook

Edoardo Charbon, Claudio Bruschini, Ivan Michel Antolovic, Samuel Burri, Harald Arjan Robert Homulle

2019