Êtes-vous un étudiant de l'EPFL à la recherche d'un projet de semestre?
Travaillez avec nous sur des projets en science des données et en visualisation, et déployez votre projet sous forme d'application sur Graph Search.
Comprehensive and cGMP suitable bioprocess monitoring is still a challenge in microbial fermn. and cell culture process development. This paper discusses the exploitation of in-situ mid-IR spectroscopy in combination with partial least-squares anal. to monitor carbohydrate, amino acid, org. acid, pH, temp., and biomass content of Saccharomyces Cerevisiae, Phaffia rhodozyma, and CHO cell cultures. Reliability of the monitored values will be discussed for potential application in cGMP environments along with case studies to increase the productivity by using the information for controlling the processes. [on SciFinder (R)]
Luc Reymond, Fabien Kuttler, Milena Maria Schuhmacher, Daria Korotkova, Manon Sandra Bardyn, Triana Amen
Mahmut Selman Sakar, Ece Özelçi, Berna Ayse Özkale Edelmann, Christina Myra Tringides
Jérôme Waser, Eliott Hugo Joran Le Du, Marion Marie-Agnès Garreau