Publication
Biologically adressable mono- and bilayer structures by templates of sulfur-bearing molecules
Publications associées (58)
Second harmonic scattering of water in a biological context
Water is one of the most abundant molecules in the universe. It forms a hydrogen bond network with unique structure and dynamics. Hydrogen bonding is highly relevant to many biological processes including membrane formation, protein folding, adsorption, an ...
EPFL2022Passive and active ion permeation through lipid bilayers investigated by second harmonic water imaging
Lipid membranes are complex and dynamic systems which are known to mediate signaling processes between cells and their environment. To do this multiple ion channels and pumps are involved in controlling the in- and out-flux of various ions (K+, Na+, Mg2+, ...
EPFL2021S-acylation by ZDHHC20 targets ORAI1 channels to lipid rafts for efficient Ca2+ signaling by Jurkat T cell receptors at the immune synapse
Françoise Gisou van der Goot Grunberg, Laurence Gouzi Abrami
Efficient immune responses require Ca2+ fluxes across ORAI1 channels during engagement of T cell receptors (TCR) at the immune synapse (IS) between T cells and antigen presenting cells. Here, we show that ZDHHC20-mediated S-acylation of the ORAI1 channel a ...
eLIFE SCIENCES PUBL LTD2021Soft matter probed by nonlinear scattering: self-assembly, interfaces, hydration, and long-range order
All organisms are made to a large extent of soft matter - macromolecules such as proteins and polysaccharides, or assemblies of small molecules such as lipids embedded in an aqueous environment. Understanding the role of order in soft matter presents a cha ...
EPFL2020The role of xanthophylls in the supramolecular organization of the photosynthetic complex LHCII in lipid membranes studied by high-resolution imaging and nanospectroscopy
Giovanni Dietler, Jiangtao Zhou
The xanthophyll cycle is a regulatory mechanism operating in the photosynthetic apparatus of plants. It consists of the conversion of the xanthophyll pigment violaxanthin to zeaxanthin, and vice versa, in response to light intensity. According to the curre ...
ELSEVIER2020Dynamic Imaging of Lipid Membranes by Means of Water
Lipid membranes are self-assembled structures whose composition determines the properties of membranes of cells and organelles. The molecular level understanding of lipid membranes is based on spectroscopy and MD simulations of lipid monolayer systems. As ...
EPFL2019Selective Localization of Hierarchically Assembled Particles to Plasma Membranes of Living Cells
Francesco Stellacci, Randy Patrick Carney
Particles that preferentially partition to a specific cellular subunit, such as the nucleus, mitochondria, or the cytoskeleton, are of relevance to a number of applications, including drug delivery, genetic manipulation, or self-assembly. Here, hierarchica ...
WILEY-V C H VERLAG GMBH2019Fixed DNA Molecule Arrays for High-Throughput Single DNA-Protein Interaction Studies
The DNA Curtains assay is a recently developed experimental platform for protein-DNA interaction studies at the single-molecule level that is based on anchoring and alignment of DNA fragments. The DNA Curtains so far have been made by using chromium barrie ...
AMER CHEMICAL SOC2019