Bioorthogonal chemistry in bioluminescence imaging

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Silicon-on-Insulator Technology for Bioluminescence Imaging and Application to a Switching Photodetector

Maher Kayal, Adil Koukab, Denis Sallin, Nisrina Abdo

This paper analyzes some advantages of Silicon-on-Insulator (SOI) based photodetectors for bioluminescence imaging. It shows that SOI based sensors not only solve the bulk carriers problem, it can also act as a very selective spectral filter by acting as a ...

Ieee2015

Bioluminescence imaging of small biomolecules

Aurélien Godinat, Riccardo Sinisi, Elena Goun, Grigory Karateev, Ghyslain Martial Alain Budin, Aleksandra Konovalova, Jens Tomas Frigell

The invention relates to a technique to detect small molecules using Bioluminescence imaging (BLI) to image and quantify non-invasively, in vitro and in vivo,intracellular metabolite fluxes and which can be applied to azido-modified compounds, such as azid ...

2014

Bioluminescent and micro-computed tomography imaging of bone repair induced by fibrin-binding growth factors

Jeffrey Alan Hubbell, Mikaël Martino

In this work we have evaluated the capacity of bone morphogenetic protein-2 (BMP-2) and fibrin-binding platelet-derived growth factor-BB (PDGF-BB) to support cell growth and induce bone regeneration using two different imaging technologies to improve the u ...

Elsevier Sci Ltd2014

A Biocompatible in Vivo Ligation Reaction and Its Application for Noninvasive Bioluminescent Imaging of Protease Activity in Living Mice

Douglas Hanahan, Aurélien Godinat, Ke Cheng, Gennady Nikitin

The discovery of biocompatible reactions had a tremendous impact on chemical biology, allowing the study of numerous biological processes directly in complex systems. However, despite the fact that multiple biocompatible reactions have been developed in th ...

Amer Chemical Soc2013

Functional and Structural Imaging with Optical Coherence Microscopy : Principles & Applications

Arno Pino Bouwens

Fluorescence microscopy techniques are well established research tools and have proven their use in a large variety of biomedical applications. Microscopic molecular contrast is achieved by imaging fluorescent dyes that bind specifically to a molecule of i ...

EPFL2013

Application of a New Sensing Principle for Photoacoustic Imaging of Point Absorbers

Dimitri Nestor Alice Van De Ville, Thierry Blu, Zafer Dogan, Ivana Jovanovic

Photoacoustic tomography (PAT) is a hybrid imaging method, which combines ultrasonic and optical imaging modalities, in order to overcome their respective weaknesses and to combine their strengths. It is based on the reconstruction of optical absorption pr ...

Spie-Int Soc Optical Engineering2013

Eigensensing And Deconvolution For The Reconstruction Of Heat Absorption Profiles From Photoacoustic Tomography Data

Dimitri Nestor Alice Van De Ville, Thierry Blu, Zafer Dogan

Photoacoustic tomography (PAT) is a relatively recent imaging modality that is promising for breast cancer detection and breast screening. It combines the high intrinsic contrast of optical radiation with acoustic imaging at submillimeter spatial resolutio ...

Ieee2013

IMAGING The fog clears

Demetri Psaltis

A technique has been developed to image a fluorescent object hiding behind a light-scattering screen without the need for a detector behind the screen. The approach could find applications in imaging biological tissue. ...

Nature Publishing Group2012

Real-Time Bioluminescence Imaging of Glycans on Live Cells

Cell-surface glycans are attractive targets for molecule imaging due to their reflection of cellular processes associated with development and disease progression. In this paper, we describe the design, synthesis, and biological application of a new phosph ...

American Chemical Society2010

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