Highly enantio- and diastereoselective inverse electron demand hetero-Diels-Alder reaction
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The first method for the [3 + 2] annulation of donor acceptor aminocyclopropanes with aldehydes is reported. The reaction is catalyzed by iron trichlorlde on alumina in yields up to 99% and with excellent cis selectivities (up to >20:1) and represents a st ...
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The first enantiospecific [3+2] annulation of D-A amino-cyclopropanes with ketones is reported herein (see scheme; Phth = phthaloyl). The reaction is catalyzed by 5 mol % of tin(IV) chloride at -78 °C and gives aminotetra-hydrofurans bearing a C5-quaternar ...
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Given a geometrically unirational variety over an infinite base field, we show that every finite separable extension of the base field that splits the variety is the residue field of a closed point. As an application, we obtain a characterization of functi ...
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