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Dual Valorization of Lignin as a Versatile and Renewable Matrix for Enzyme Immobilization and (Flow) Bioprocess Engineering

Publications associées (27)

Optimality principles for the analysis of biological processes across scales: From enzyme kinetics to microbiome dynamics

Microorganisms are essential for life on Earth, performing key roles in numerous biological processes. Their influence extends across a wide spectrum, from human health and ecological balance to advancements in biotechnology and industrial applications. Th ...

EPFL2024

Organ-specific biotransformation in salmonids: Insight into intrinsic enzyme activity and biotransformation of three micropollutants

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Aquatic ecosystems continue to be threatened by chemical pollution. To what extent organisms are able to cope with chemical exposure depends on their ability to display mechanisms of defense across different organs. Among these mechanisms, biotransformatio ...

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An explainability framework for deep learning on chemical reactions exemplified by enzyme-catalysed reaction classification

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Assigning or proposing a catalysing enzyme given a chemical or biochemical reaction is of great interest to life sciences and chemistry alike. The exploration and design of metabolic pathways and the challenge of finding more sustainable enzyme-catalysed a ...

2023

Optimal enzyme utilization suggests that concentrations and thermodynamics determine binding mechanisms and enzyme saturations

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One of the main challenges hampering the development of kinetic models is the lack of kinetic parameters for many enzymatic reactions. Here, the authors introduce a framework to explore the catalytically optimal operating conditions of any complex enzyme m ...

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Investigation of Carboxylic Acid Isosteres and Prodrugs for Inhibition of the Human SIRT5 Lysine Deacylase Enzyme

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Sirtuin 5 (SIRT5) is a protein lysine deacylase enzyme that regulates diverse biology by hydrolyzing epsilon-N-carboxyacyllysine posttranslational modifications in the cell. Inhibition of SIRT5 has been linked to potential treatment of several cancers but ...

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Amino acids are some of the main building stones of life used in a variety of biological processes, such as protein synthesis, energy metabolism or even as precursors for hormone synthesis. How-ever, some of them also participate and coordinate certain cel ...

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The gut microbiome, often referred to as "super organ", comprises up to a hundred trillion microorganisms, and the species diversity may vary from person to person. They perform a decisive role in diverse biological functions related to metabolism, immunit ...

ELSEVIER2021

Dual Valorization of Lignin as a Versatile and Renewable Matrix for Enzyme Immobilization and (Flow) Bioprocess Engineering

Optimality principles for the analysis of biological processes across scales: From enzyme kinetics to microbiome dynamics

Organ-specific biotransformation in salmonids: Insight into intrinsic enzyme activity and biotransformation of three micropollutants

An explainability framework for deep learning on chemical reactions exemplified by enzyme-catalysed reaction classification

Optimal enzyme utilization suggests that concentrations and thermodynamics determine binding mechanisms and enzyme saturations

Hypervalent Iodine: New Reagents and Functionalization of Peptides

Model-based scale-up of a continuously operated consolidated bioprocess based on a microbial consortium for the production of ethanol

Investigation of Carboxylic Acid Isosteres and Prodrugs for Inhibition of the Human SIRT5 Lysine Deacylase Enzyme

Dissecting the role of the asparagine synthesis in acute liver injury

Probiotics and gut microbiome-Prospects and challenges in remediating heavy metal toxicity

Graph Chatbot

Optimality principles for the analysis of biological processes across scales: From enzyme kinetics to microbiome dynamics

Organ-specific biotransformation in salmonids: Insight into intrinsic enzyme activity and biotransformation of three micropollutants

An explainability framework for deep learning on chemical reactions exemplified by enzyme-catalysed reaction classification

Optimal enzyme utilization suggests that concentrations and thermodynamics determine binding mechanisms and enzyme saturations

Hypervalent Iodine: New Reagents and Functionalization of Peptides

Model-based scale-up of a continuously operated consolidated bioprocess based on a microbial consortium for the production of ethanol

Investigation of Carboxylic Acid Isosteres and Prodrugs for Inhibition of the Human SIRT5 Lysine Deacylase Enzyme

Dissecting the role of the asparagine synthesis in acute liver injury

Probiotics and gut microbiome-Prospects and challenges in remediating heavy metal toxicity

Organohalide respiration in Firmicutes: energy metabolism and transcription regulation

Organohalide respiration in Firmicutes: energy metabolism and transcription regulation