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Rostral and caudal pharyngeal arches share a common neural crest ground pattern

Publications associées (29)

Development of a Robotic Microsurgeon for Embryonic Research

Understanding how biological matter takes its shape is instrumental to biology, bioengineering, medicine, and bioinspired engineering. Gaining information on the principles of morphogenesis could enable clinicians to correct developmental abnormalities, ev ...

EPFL2023

How are cells instructed to form somite boundaries by the zebrafish segmentation clock?

Olivier François Venzin

In vertebrate embryos, the elongating body axis is patterned via the sequential and rhyth-mic production of segments from a posterior unsegmented tissue called the presomitic mesoderm (PSM). This process is controlled by a population of cellular oscillator ...

EPFL2023

Preparation of Single-Somite Explants from Zebrafish Embryos

Andrew Charles Oates, Sundar Ram Naganathan

The body axis of vertebrate embryos is periodically subdivided into 3D multicellular units called somites. While genetic oscillations and molecular prepatterns determine the initial length-scale of somites, mechanical processes have been implicated in sett ...

JOURNAL OF VISUALIZED EXPERIMENTS2022

Re:Crete - A Footbridge made of Reused Concrete Blocks

Corentin Jean Dominique Fivet, Maléna Bastien Masse, Célia Marine Küpfer, Jan Friedrich Georg Brütting, Julie Rachel Devènes

Today, concrete is the most widely used construction material worldwide. Strong, versatile, durable, and vector of economic development, this exceptional material is also the principal cause of greenhouse-gas emissions, material depletion and waste generat ...

Asociación Española de Ingeniería Estructura2022

Towards engineering an artificial neural tube

Jisoo Park

In this thesis, I present a self-organizing neural tube organoid that is strikingly similar in morphology, cell-type composition, and patterning to the mouse embryonic neural tube. When exposed to a sequence of epiblast culture conditions and neural differ ...

EPFL2021

Conceptual design of 1000 m scale steel-UHPFRC composite truss arch bridge

Jieping Zhu, Ping Zhu, Xiujiang Shen

Excessive self-weight and difficulty in construction are the main issues confronted by super-long-span arch bridges. To address these issues, a conceptual design of steel-ultra-high performance fibre-reinforced concrete (UHPFRC) composite truss arch bridge ...

ELSEVIER SCI LTD2021

Mesomelic dysplasias associated with the HOXD locus are caused by regulatory reallocations

Denis Duboule, Christopher Chase Bolt, Lucille Delisle

Mesomelic dysplasia, a severe shortening and bending of the limb, has been linked to rearrangements in the HoxD cluster in humans and mice. Here the authors engineer a 1 Mb inversion including the HoxD gene cluster and use this model to provide a mechanist ...

Nature Portfolio2021

In vitro modeling of early mouse development

Mehmet Ugur Girgin

Previous attempts to recapitulate embryogenesis in a developmentally relevant context started with aggregates composed of a few thousand ESCs, termed embryoid bodies (EB), that upon induction of differentiation reveal a surprising level of autonomous cell ...

EPFL2020

HOX13-dependent chromatin accessibility underlies the transition towards the digit development program

Alexandre Gauthier Aurèle Mayran

Hox genes encode transcription factors (TFs) that establish morphological diversity in the developing embryo. The similar DNA-binding motifs of the various HOX TFs contrast with the wide-range of HOX-dependent genetic programs. The influence of the chromat ...

Nature Research2020

Rostral and caudal pharyngeal arches share a common neural crest ground pattern

Development of a Robotic Microsurgeon for Embryonic Research

How are cells instructed to form somite boundaries by the zebrafish segmentation clock?

Preparation of Single-Somite Explants from Zebrafish Embryos

Re:Crete - A Footbridge made of Reused Concrete Blocks

Towards engineering an artificial neural tube

Conceptual design of 1000 m scale steel-UHPFRC composite truss arch bridge

Mesomelic dysplasias associated with the HOXD locus are caused by regulatory reallocations

In vitro modeling of early mouse development

HOX13-dependent chromatin accessibility underlies the transition towards the digit development program

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Development of a Robotic Microsurgeon for Embryonic Research

How are cells instructed to form somite boundaries by the zebrafish segmentation clock?

Preparation of Single-Somite Explants from Zebrafish Embryos

Re:Crete - A Footbridge made of Reused Concrete Blocks

Towards engineering an artificial neural tube

Sequential in cis mutagenesis in vivo reveals various functions for CTCF sites at the mouse HoxD cluster

Conceptual design of 1000 m scale steel-UHPFRC composite truss arch bridge

Mesomelic dysplasias associated with the HOXD locus are caused by regulatory reallocations

In vitro modeling of early mouse development

HOX13-dependent chromatin accessibility underlies the transition towards the digit development program

Sequential in cis mutagenesis in vivo reveals various functions for CTCF sites at the mouse HoxD cluster