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The MIDI Degradation Toolkit: Symbolic Music Augmentation and Correction

Publications associées (26)

Resolving bacterial cell biology: from replisome dynamics to cell wall synthesis

Bacteria are ubiquitous single cellular organisms. Compared to eukaryotic cells, bacteria have two unique characteristics: the membrane-less nucleoid and the cell wall built of peptidoglycan (PG). In most bacteria, a single circular chromosome is compacted ...

EPFL2024

Sequential and directional insulation by conserved CTCF sites underlies the Hox timer in stembryos

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Temporal activation of Hox genes in mouse pseudo-embryos in vitro initiates at the anterior part of the cluster and is accompanied by asymmetric loading of cohesin. Posterior CTCF sites then successively act as transient insulators, regulating the timed tr ...

NATURE PORTFOLIO2023

On matching data and model in LF-MMI-based dysarthric speech recognition

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In light of steady progress in machine learning, automatic speech recognition (ASR) is entering more and more areas of our daily life, but people with dysarthria and other speech pathologies are left behind. Their voices are underrepresented in the trainin ...

EPFL2023

Biochemistry of Aminoacyl tRNA Synthetase and tRNAs and Their Engineering for Cell-Free and Synthetic Cell Applications

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Cell-free biology is increasingly utilized for engineering biological systems, incorporating novel functionality, and circumventing many of the complications associated with cells. The central dogma describes the information flow in biology consisting of t ...

FRONTIERS MEDIA SA2022

A satellite DNA array barcodes chromosome 7 and regulates totipotency via ZFP819

Didier Trono, Gabriela Ecco, Helen Mary Rowe

Mammalian genomes are a battleground for genetic conflict between repetitive elements and KRAB-zinc finger proteins (KZFPs). We asked whether KZFPs can regulate cell fate by using ZFP819, which targets a satellite DNA array, ZP3AR. ZP3AR coats megabase reg ...

2022

Towards an artificial cell: Development of a system which self-regenerates the protein components of the PURE system in microfluidic reactors

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Thanks to recent advancements in synthetic biology, the dream of creating a synthetic cell has become feasible. However, due to its inherent complexity, one of the fundamental functions of all living systems, i.e., self-replication, remains to be introduce ...

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Cell-free gene-regulatory network engineering with synthetic transcription factors

Sebastian Maerkl, Zoe Newell Swank, Nadanai Laohakunakorn

Gene-regulatory networks are ubiquitous in nature and critical for bottom-up engineering of synthetic networks. Transcriptional repression is a fundamental function that can be tuned at the level of DNA, protein, and cooperative protein-protein interaction ...

National Academy of Sciences2019

Quantitative single cell dynamics of signaling and transcriptional response in mammalian cells

Onur Tidin

Cells live in ever-changing environments, thereby facing a variety of dynamic environmental signals. Environmental stimuli elicit intracellular responses through signaling pathways, which converge on transcriptional activation or repression of target genes ...

EPFL2018

Modeling and analysis of parts and devices of genetic regulation

Yves Berset

DNA encrypts the composition of the cellular material that is synthesized through transcription and translation. Never-theless, gene regulation mechanisms determine the final amount of transcribed and translated material. Transcription factors (TF) are a c ...

EPFL2018

The MIDI Degradation Toolkit: Symbolic Music Augmentation and Correction

Resolving bacterial cell biology: from replisome dynamics to cell wall synthesis

Sequential and directional insulation by conserved CTCF sites underlies the Hox timer in stembryos

On matching data and model in LF-MMI-based dysarthric speech recognition

Biochemistry of Aminoacyl tRNA Synthetase and tRNAs and Their Engineering for Cell-Free and Synthetic Cell Applications

A satellite DNA array barcodes chromosome 7 and regulates totipotency via ZFP819

Towards an artificial cell: Development of a system which self-regenerates the protein components of the PURE system in microfluidic reactors

Cell-free gene-regulatory network engineering with synthetic transcription factors

Quantitative single cell dynamics of signaling and transcriptional response in mammalian cells

Modeling and analysis of parts and devices of genetic regulation

Graph Chatbot

Resolving bacterial cell biology: from replisome dynamics to cell wall synthesis

Sequential and directional insulation by conserved CTCF sites underlies the Hox timer in stembryos

On matching data and model in LF-MMI-based dysarthric speech recognition

Biochemistry of Aminoacyl tRNA Synthetase and tRNAs and Their Engineering for Cell-Free and Synthetic Cell Applications

A satellite DNA array barcodes chromosome 7 and regulates totipotency via ZFP819

Towards an artificial cell: Development of a system which self-regenerates the protein components of the PURE system in microfluidic reactors

Opposing chromatin remodelers control transcription initiation frequency and start site selection

Cell-free gene-regulatory network engineering with synthetic transcription factors

Quantitative single cell dynamics of signaling and transcriptional response in mammalian cells

Modeling and analysis of parts and devices of genetic regulation

Opposing chromatin remodelers control transcription initiation frequency and start site selection