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Physiological Adaptations to Sugar Intake: New Paradigms from Drosophila melanogaster

Publications associées (28)

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Meeting our Makers: Uncovering the cis-regulatory activity of transposable elements using statistical learning

Cyril David Son-Tuyên Pulver

The adaptation of organisms to their environment depends on the innovative potential inherent to genetic variation. In complex organisms such as mammals, processes like development and immunity require tight gene regulation. Complex forms emerge more often ...

EPFL2024

Beyond the average consumer: Mapping the potential of demand-side management among patterns of appliance usage

Claudia Rebeca Binder Signer, Matteo Barsanti, Selin Yilmaz

To support the decarbonisation of the power sector and offset the volatility of a system with high levels of renewables, there is growing interest in residential Demand-Side Management (DSM) solutions. Traditional DSM strategies require consumers to active ...

2024

Design and assessment of an evaporating water-cooled methanation reactor for a SOE-based power-to-methane system

Philippe Aubin

The transition towards clean renewable energy sources, where wind and solar are prone to variation, requires adequate energy storage. Power-to-methane (PtM) systems can be part of the solution. Specifically, solid-oxide-electrolyser (SOE) based PtM systems ...

EPFL2024

Decoding Chromatin Ubiquitylation: A Chemical Biology Perspective

Beat Fierz, Pauline Franz

Since Strahl and Allis proposed the "language of covalent histone modifications", a host of experimental studies have shed light on the different facets of chromatin regulation by epigenetic mechanisms. Initially proposed as a concept for controlling gene ...

Academic Press Ltd- Elsevier Science Ltd2024

Hippo-YAP/TAZ signalling coordinates adipose plasticity and energy balance by uncoupling leptin expression from fat mass

Johan Auwerx, Xiaoxu Li, Maroun Bou Sleiman, Jun Yong Kim, Yoo Hoon Kim

Adipose tissues serve as an energy reservoir and endocrine organ, yet the mechanisms that coordinate these functions remain elusive. Here, we show that the transcriptional coregulators, YAP and TAZ, uncouple fat mass from leptin levels and regulate adipocy ...

Nature Portfolio2024

Optimality principles for the analysis of biological processes across scales: From enzyme kinetics to microbiome dynamics

Asli Sahin

Microorganisms are essential for life on Earth, performing key roles in numerous biological processes. Their influence extends across a wide spectrum, from human health and ecological balance to advancements in biotechnology and industrial applications. Th ...

EPFL2024

Inheritance of H3K9 methylation regulates genome architecture in Drosophila early embryos

Fides Zenk

Constitutive heterochromatin is essential for transcriptional silencing and genome integrity. The establishment of constitutive heterochromatin in early embryos and its role in early fruitfly development are unknown. Lysine 9 trimethylation of histone H3 ( ...

Springernature2024

Modeling, analysis, and design of complex biological networks

Mohammadomid Oftadeh

Automating experimental procedures has resulted in an unprecedented increase in the volume of generated data, which, in turn, has caused an accumulation of unprocessed data. As a result, the need to develop tools to analyze data systematically has been ris ...

EPFL2023

Importance of hydropower reservoirs and dams in Europe to mitigate the energy crisis and to serve as a catalyst and enabler for the Green Deal

Anton Schleiss

Hydropower has a long tradition in Europe and contributed significantly during the last century to industrial development and welfare in most of the countries in Europe. The ambitious plan for an energy transition in Europe now seeks to achieve a lowcarbon ...

CRC Press/Balkema2023

Flexible High Power Electronics Solutions for Hydro-Power Applications

Philippe Alexandre Bontemps

The current global energy landscape is characterized by an increasing demand for affordable and sustainable energy sources, leading to an ever increasing integration of intermittent renewable energy resources into the grid. The intermittent nature of these ...

EPFL2023

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Optimality principles for the analysis of biological processes across scales: From enzyme kinetics to microbiome dynamics

Asli Sahin

EPFL2024

Inheritance of H3K9 methylation regulates genome architecture in Drosophila early embryos

Fides Zenk

Springernature2024

Modeling, analysis, and design of complex biological networks

Mohammadomid Oftadeh

EPFL2023

Importance of hydropower reservoirs and dams in Europe to mitigate the energy crisis and to serve as a catalyst and enabler for the Green Deal

Anton Schleiss

CRC Press/Balkema2023

Flexible High Power Electronics Solutions for Hydro-Power Applications

Philippe Alexandre Bontemps

EPFL2023