Lymphatica

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Publications associées (29)

Tumor-associated factors are enriched in lymphatic exudate compared to plasma in metastatic melanoma patients

Davide Demurtas, Melody Swartz, Romain Hamelin, Lambert Charles François Potin, Patricia Corthésy Henrioud, Natacha Anne-Sophie Bordry, Maria Anna Sofia Broggi, Léa Maillat, Alexandre Harari

Liquid biopsies allow monitoring of cancer progression and detection of relapse, but reliable biomarkers in melanoma are lacking. Because secreted factors preferentially drain to lymphatic vessels before dilution in the blood, we hypothesized that lymph sh ...

ROCKEFELLER UNIV PRESS2019

Rapid evaluation of bioactive Ti-based surfaces using an in vitro titration method

Paul Bowen, Jacques Lemaître, Weitian Zhao

The prediction of implant behavior in vivo by the use of easy-to-perform in vitro methods is of great interest in biomaterials research. Simulated body fluids (SBFs) have been proposed and widely used to evaluate the bone-bonding ability of implant materia ...

Springer2019

Spatiotemporal stimulation strategies in neuroprostheses to improve locomotion after spinal cord injury

Jérôme Gandar

Spinal cord injury (SCI) disrupts communication within central nervous system and lead to range of neurological disorders including paralysis. Current rehabilitation strategies to restore locomotion are poorly effective in people with severe SCI. Epidural ...

EPFL2019

Multiple roles of lymphatic vessels in peripheral lymph node development

Borja Prat Luri, Esther Bovay, Ann-Helen Willrodt

The mammalian lymphatic system consists of strategically located lymph nodes (LNs) embedded into a lymphatic vascular network. Mechanisms underlying development of this highly organized system are not fully understood. Using highresolution imaging, we show ...

2018

Lymphatic vessel density is associated with CD8(+) T cell infiltration and immunosuppressive factors in human melanoma

Melody Swartz, Olivier Michielin, Manuel Andreas Fankhauser, Timothy Murray, Natacha Anne-Sophie Bordry, Maria Anna Sofia Broggi, Esther Danenberg

Increased density of tumor-associated lymphatic vessels correlates with poor patient survival in melanoma and other cancers, yet lymphatic drainage is essential for initiating an immune response. Here we asked whether and how lymphatic vessel density (LVD) ...

TAYLOR & FRANCIS INC2018

Knee Implant Loosening Detection: A Vibration Analysis Investigation

Kamiar Aminian, Arash Arami, Hossein Rouhani

Knee implant loosening is mainly caused by the weakness of the prosthesis-bone interface and is the main reason for surgical revisions. However, pre-operative diagnosis is difficult due to lack of accurate tests. In this study, we developed a vibration-bas ...

Springer Verlag2018

Long-term functionality of a soft electrode array for epidural spinal cord stimulation in a minipig model

Stéphanie Lacour, Grégoire Courtine, Giuseppe Schiavone, Jocelyne Bloch, Marco Capogrosso, Nicolas Vachicouras, Fabien Bertrand Paul Wagner, Florian Dylan Fallegger, Xiaoyang Kang, Beatrice Barra

Long-term biointegration of man-made neural interfaces is influenced by the mechanical properties of the implant materials. Substantial experimental work currently aims at replacing conventional hard implant materials with soft alternatives that can favour ...

IEEE2018

An area and power efficient on-the-fly LBCS transformation for implantable neuronal signal acquisition systems

Volkan Cevher, Cosimo Aprile, Yusuf Leblebici, Luca Baldassarre

A power and area effcient hardware encoding system tailored for wireless implantable applications is presented. Constant medical monitoring allowed by implantable devices is the most relevant alternative to current bulky monitoring systems, which, in case ...

2018

An area and power efficient on-the-fly LBCS transformation for implantable neuronal signal acquisition systems

Volkan Cevher, Cosimo Aprile, Yusuf Leblebici, Luca Baldassarre

A power and area efficient hardware encoding system tailored for wireless implantable applications is presented. Constant medical monitoring allowed by implantable devices is the most relevant alternative to current bulky monitoring systems, which, in case ...

ASSOC COMPUTING MACHINERY2018

Transcellular Pathways in Lymphatic Endothelial Cells Regulate Changes in Solute Transport by Fluid Stress

Melody Swartz, Marco Pisano, Witold Waldemar Kilarski, Esra Güç, Valentina Triacca

Rationale: The transport of interstitial fluid and solutes into lymphatic vessels is important for maintaining interstitial homeostasis and delivering antigens and soluble factors to the lymph node for immune surveillance. Transendothelial transport across ...

Lippincott Williams & Wilkins2017

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