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This lecture covers the use of robotics in lower limb rehabilitation and assistance, focusing on devices and strategies for motor rehabilitation. It discusses the application of science and technology to improve the mobility of individuals with various disorders, such as spinal cord injuries, strokes, and neurodegenerative diseases. The lecture explores the role of robotics in mobilization, evaluation, and interaction during the rehabilitation process, showcasing devices like the Lokomat and BCI-based rehabilitation strategies. It also delves into the development of sitting position devices and powered lower limb exoskeletons, highlighting the importance of parallel kinematics and force amplification. The lecture concludes by emphasizing the potential of lower limb exoskeletons as assistive technologies for daily living activities.