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This lecture introduces the immune system, focusing on how cells and organisms defend against pathogens. Topics include physical and chemical barriers, innate and adaptive immunity, immune cell functions, and the complement system. The instructor explains the roles of neutrophils, macrophages, mast cells, and dendritic cells in recognizing and eliminating pathogens. The lecture also covers the activation pathways of the complement system and the inflammatory response. Students learn about the immune disorders, immune deficiencies, and autoimmune diseases. Overall, the lecture provides a comprehensive overview of the defense mechanisms employed by the immune system.