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This lecture covers the immune system, focusing on T cells, antigen presentation, and the mechanisms by which cells defend themselves. It explains the generation of T cell receptors in the thymus, the production of different subsets of T cells, and the functions of cytotoxic T cells. The presentation also delves into the major histocompatibility complex (MHC) proteins, their role in antigen presentation, and the activation of T cells. Additionally, it discusses the immune response to infected cells, the process of apoptosis triggered by cytotoxic T cells, and the principles and types of vaccines. The lecture concludes with an overview of vaccination history and the development of vaccines against pathogens.