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This lecture introduces ion chromatography (IC), a liquid chromatography technique dedicated to analyzing ionic and ionizable molecules. It covers the separation mechanisms, columns, eluents, detectors, and stationary phases used in IC. The lecture also discusses the retention principles for anions and cations, as well as the use of gradients for complex mixtures. Various examples of IC separations are presented, showcasing the versatility of IC in analyzing different types of ions and compounds. The importance of eluent purity, conductivity, and temperature control in optimizing IC separations is emphasized.