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This lecture covers the structural organization of proteins, including primary, secondary, tertiary, and quaternary structures. It also discusses various proteins' functions in cells, such as actin, collagen, laminin, transmembrane proteins, and growth factors. Additionally, it explores the cytoskeleton's role in maintaining cell shape and organization, the components of the cytoskeleton, and the tensegrity model. The lecture further delves into materials design for tissue engineering, focusing on scaffold parameters like topography, stiffness, and cell adhesion. Ligands and receptors are also explained, using the example of caffeine and adenosine binding to the same receptor and the implications of caffeine consumption on alertness.