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This lecture covers the regulation of the cardiovascular system, including the role of sympathetic and parasympathetic systems, intracellular signaling, the cardiac cycle, the Frank-Starling law, determinants of cardiac output, vascular flow, blood pressure regulation, and vascular resistance. It also discusses the electrical activity of the heart, the impact of sympathetic and parasympathetic systems on heart activity, and the equations governing pressure, flow, and resistance in the cardiovascular system.