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This lecture covers the use of PCR analysis to differentiate between meat origins, focusing on the example of detecting horse meat in beef lasagna. The instructor explains the importance of the last base in primers, the process of PCR amplification, and the significance of microsatellites in determining the origin of fish species. By analyzing the number of copies of microsatellites, one can distinguish between fish populations from different regions, such as Estonia and Laclément. The lecture emphasizes the application of PCR in food authenticity testing and population genetics, showcasing how genetic variations can reveal the true origin of food products.