Lecture

Tumor Suppressor p53

Description

This lecture covers the tumor suppressor gene p53, its role in regulating cell proliferation, DNA damage response, and cancer development. Topics include p53 structure, function, regulation, and its interaction with MDM2 and ARF. The lecture also discusses the impact of p53 mutations on cell cycle control, apoptosis, and senescence, as well as the implications for cancer development and therapeutic strategies.

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