Are you an EPFL student looking for a semester project?
Work with us on data science and visualisation projects, and deploy your project as an app on top of Graph Search.
This lecture covers the tumor suppressor gene p53, its role in regulating cell proliferation, DNA damage response, and cancer development. Topics include p53 structure, function, regulation, and its interaction with MDM2 and ARF. The lecture also discusses the impact of p53 mutations on cell cycle control, apoptosis, and senescence, as well as the implications for cancer development and therapeutic strategies.