Catalytic Asymmetric Reactions in Organic Chemistry

This lecture by the instructor covers the principles and applications of catalytic asymmetric reactions in organic chemistry, focusing on ligands, metals, and reaction mechanisms. It includes classical examples, recent developments, and the importance of asymmetric catalysis in pharmaceuticals. The lecture also discusses key parameters for catalysis efficiency and asymmetric induction, as well as different modes of asymmetric induction such as desymmetrization and kinetic resolution. Various examples of asymmetric reactions, including Aldol and Allylation reactions, are presented with detailed mechanisms and catalyst designs. The lecture concludes with a discussion on the classification of catalytic asymmetric reactions based on catalysts, reactions, chiral elements, and catalytic principles.