This lecture focuses on the design of distillation columns, specifically addressing the use of partial condensers and total reboilers. The instructor begins by discussing the operation of a distillation column, emphasizing the importance of maintaining the composition of vapor and liquid phases. The lecture introduces the concept of a partial condenser, which allows for the separation of vapor and liquid phases without altering the vapor composition. The instructor explains how this design is particularly useful in applications where the distillate is desired in vapor form, such as in refineries. The lecture also covers the impact of these designs on equilibrium plots and operating lines, illustrating how to plot compositions and understand their relationships. Additionally, the instructor explores the case of multiple feeds and outlets, detailing how to manage varying feed qualities and their effects on the distillation process. The lecture concludes with a discussion on overall tray efficiency and Murphee stage efficiency, providing insights into practical considerations in distillation column design.