Catalytic Asymmetric Reactions in Organic Chemistry

This lecture covers the summary of chapters 3.1 and 3.2, focusing on catalytic asymmetric reactions in organic chemistry. It discusses the activation of electrophiles other than carbonyl/imines, the use of hypervalent iodine reagents, and various catalytic reactions such as oxidative spirolactonization and diacetoxylation of olefins. The lecture also delves into the catalytic asymmetric Staudinger Aza-Wittig reaction, activation of allylic systems, direct allylic substitution, and sources of enantiodiscrimination. Furthermore, it explores ligands and mechanisms, stereoinduction models, desymmetrization of meso-substrates, and kinetic resolution of propargylic alcohols. The lecture concludes with discussions on chiral acylation, dynamic kinetic resolution of esters, and the resolution of cyclic amines via azolium intermediates.