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This lecture explores the physical description of biological systems, focusing on embryonic tissue mechanics and tissue fluidization during zebrafish tailbud extension. It covers challenges in modeling biological tissues, key aspects in modeling embryonic tissue, and the solid-fluid transitions in equilibrium. The instructor discusses the dynamics of rounded and anisotropic nuclei, subcellular elements influencing tissue mechanics, and the activity-induced transitions in embryonic tissues. The lecture concludes with a summary of the nuclear jamming in zebrafish brain tissues, acknowledging the Campàs group's contributions. Various models and experimental results are presented to understand the emergent properties of embryonic tissues.
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