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This lecture by the instructor delves into the intricate process of tissue patterning, focusing on the development of complex organ patterns through cell-to-cell interactions and morphogen gradients. The presentation covers topics such as tissue engineering, scaffold design, organ regeneration, and the role of morphogens in shaping tissue structures. It explores the challenges and advancements in bioengineering functional tissues and organs, emphasizing the importance of understanding cell-to-cell and cell-ECM interactions. The lecture also discusses the concept of juxtacrine signaling, lateral inhibition, and the generation of cell type diversity and patterns through sequential induction and asymmetric division.