Person
Gabriela Garcia Rodriguez
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Toxin:antitoxin ratio sensing autoregulation of the Vibrio cholerae parDE2 module
The parDE family of toxin-antitoxin (TA) operons is ubiquitous in bacterial genomes and, in Vibrio cholerae, is an essential component to maintain the presence of chromosome II. Here, we show that transcription of the V. cholerae parDE2 (VcparDE) operon is ...
2024Alternative dimerization is required for activity and inhibition of the HEPN ribonuclease RnlA
The rnlAB toxin-antitoxin operon from Escherichia co/ifunctions as an anti-phage defense system. RnlA was identified as a member of the HEPN (Higher Eukaryotes and Prokaryotes Nucleotide-binding domain) superfamily of ribonucleases. The activity of the tox ...
OXFORD UNIV PRESS2021