Tandem mass spectrometry is a powerful technique for the identification of proteins contained in a biological sample. We present a grid-based application service for the analysis of tandem mass spectra, based on the open-source X!Tandem algorithm. The implemented parallelization strategy allows the distribution of analysis jobs to a grid of desktop PCs, utilizing their idle capacity. For this application service, a user-friendly project-oriented frontend was developed, implemented as a web-based workspace. After analysis, results are visualized and presented to the user along with a set of powerful and novel tools to allow further interpretation and evaluation of search results.
Eduardo Carrascosa Casado, Gabriel Da Silva
Thomas Rizzo, Ahmed Ben Faleh, Stephan Warnke, Priyanka Bansal, Ali H Abikhodr, Vasyl Yatsyna, Natalia Yalovenko