HIV-1 sequence diversity is affected by selection pressures arising from host genomic factors. Using paired human and viral data from 1071 individuals, we ran >3000 genome-wide scans, testing for associations between host DNA polymorphisms, HIV-1 sequence variation and plasma viral load (VL), while considering human and viral population structure. We observed significant human SNP associations to a total of 48 HIV-1 amino acid variants (p
Jacques Fellay, Zhi Ming Xu, Sina Rüeger
Jacques Fellay, Dylan Lawless, Olivier Noël Marie Naret, Christian Hammer, Sina Rüeger
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