Chromosome 3

Chromosome 3 is one of the 23 pairs of chromosomes in humans. People normally have two copies of this chromosome. Chromosome 3 spans 201 million base pairs (the building material of DNA) and represents about 6.5 percent of the total DNA in cells. The following are some of the gene count estimates of human chromosome 3. Because researchers use different approaches to genome annotation their predictions of the number of genes on each chromosome varies (for technical details, see gene prediction). Among various projects, the collaborative consensus coding sequence project (CCDS) takes an extremely conservative strategy. So CCDS's gene number prediction represents a lower bound on the total number of human protein-coding genes. Genes on human chromosome 3 The following is a partial list of genes on human chromosome 3. For complete list, see the link in the infobox on the right. Partial list of the genes located on p-arm (short arm) of human chromosome 3: Partial list of the genes located on q-arm (long arm) of human chromosome 3: The following diseases and disorders are some of those related to genes on chromosome 3: 3-Methylcrotonyl-CoA carboxylase deficiency 3q29 microdeletion syndrome Acute myeloid leukemia (AML) Alkaptonuria Arrhythmogenic right ventricular dysplasia Atransferrinemia Autism Autosomal dominant optic atrophy ADOA plus syndrome Biotinidase deficiency Blepharophimosis, epicanthus inversus and ptosis type 1 Breast/colon/lung/pancreatic cancer Brugada syndrome Castillo fever Carnitine-acylcarnitine translocase deficiency Cataracts Cerebral cavernous malformation Charcot–Marie–Tooth disease, type 2 Charcot–Marie–Tooth disease Chromosome 3q duplication syndrome Coproporphyria A location on human chromosome 3 is associated with respiratory failure and possibly with increased severity in COVID-19 Dandy–Walker syndrome Deafness Diabetes Dystrophic epidermolysis bullosa Endplate acetylcholinesterase deficiency Essential tremors Ectrodactyly, Case 4 Glaucoma, primary open angle Glycogen storage disease Hailey

Computational identification and experimental characterization of preferred downstream positions in human core promoters

Philipp Bucher, René Dreos

Author summary Transcription of genes by the RNA polymerase II enzyme initiates at a genomic region termed the core promoter. The core promoter is a regulatory region that may contain diverse short DNA sequence motifs/elements that confer specific properti ...

PUBLIC LIBRARY SCIENCE2021

Learning Intelligent Dialogs for Bounding Box Annotation

Ksenia Konyushkova, Vittorio Ferrari

We introduce Intelligent Annotation Dialogs for bounding box annotation. We train an agent to automatically choose a sequence of actions for a human annotator to produce a bounding box in a minimal amount of time. Specifically, we consider two actions: box ...

IEEE2018

Highly Reduced Genome of the New Species Mycobacterium uberis, the Causative Agent of Nodular Thelitis and Tuberculoid Scrotitis in Livestock and a Close Relative of the Leprosy Bacilli

Stewart Cole, Andrej Benjak, Charlotte Avanzi

Nodular thelitis is a chronic enzootic infection affecting dairy cows and goats. The causative agent was recently shown to be related to the leprosy-causing bacilli Mycobacterium leprae and Mycobacterium lepromatosis. In this study, the genome of this path ...

AMER SOC MICROBIOLOGY2018

Computational identification and experimental characterization of preferred downstream positions in human core promoters

Learning Intelligent Dialogs for Bounding Box Annotation

Highly Reduced Genome of the New Species Mycobacterium uberis, the Causative Agent of Nodular Thelitis and Tuberculoid Scrotitis in Livestock and a Close Relative of the Leprosy Bacilli

Graph Chatbot

Chat with Graph Search

Computational identification and experimental characterization of preferred downstream positions in human core promoters

Highly Reduced Genome of the New Species Mycobacterium uberis, the Causative Agent of Nodular Thelitis and Tuberculoid Scrotitis in Livestock and a Close Relative of the Leprosy Bacilli

Learning Intelligent Dialogs for Bounding Box Annotation