Age-related memory loss, sometimes described as "normal aging" (also spelled "ageing" in British English), is qualitatively different from memory loss associated with types of dementia such as Alzheimer's disease, and is believed to have a different brain mechanism.
Mild cognitive impairment
Mild cognitive impairment (MCI) is a condition in which people face memory problems more often than that of the average person their age. These symptoms, however, do not prevent them from carrying out normal activities and are not as severe as the symptoms for Alzheimer's disease (AD). Symptoms often include misplacing items, forgetting events or appointments, and having trouble finding words.
According to recent research, MCI is seen as the transitional state between cognitive changes of normal aging and Alzheimer's disease. Several studies have indicated that individuals with MCI are at an increased risk for developing AD, ranging from one percent to twenty-five percent per year; in one study twenty-four percent of MCI patients progressed to AD in two years and twenty percent more over three years, whereas another study indicated that the progression of MCI subjects was fifty-five percent in four and a half years. Some patients with MCI, however, never progress to AD.
Studies have also indicated patterns that are found in both MCI and AD. Much like patients with Alzheimer's disease, those with mild cognitive impairment have difficulty accurately defining words and using them appropriately in sentences when asked. While MCI patients had a lower performance in this task than the control group, AD patients performed worse overall. The abilities of MCI patients stood out, however, due to the ability to provide examples to make up for their difficulties. AD patients failed to use any compensatory strategies and therefore exhibited the difference in use of episodic memory and executive functioning.
Normal aging is associated with a decline in various memory abilities in many cognitive tasks; the phenomenon is known as age-related memory impairment (AMI) or age-associated memory impairment (AAMI).
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Ageing (or aging in American English) is the process of becoming older. The term refers mainly to humans, many other animals, and fungi, whereas for example, bacteria, perennial plants and some simple animals are potentially biologically immortal. In a broader sense, ageing can refer to single cells within an organism which have ceased dividing, or to the population of a species. In humans, ageing represents the accumulation of changes in a human being over time and can encompass physical, psychological, and social changes.
Memory is the faculty of the mind by which data or information is encoded, stored, and retrieved when needed. It is the retention of information over time for the purpose of influencing future action. If past events could not be remembered, it would be impossible for language, relationships, or personal identity to develop. Memory loss is usually described as forgetfulness or amnesia. Memory is often understood as an informational processing system with explicit and implicit functioning that is made up of a sensory processor, short-term (or working) memory, and long-term memory.
Procedural memory is a type of implicit memory (unconscious, long-term memory) which aids the performance of particular types of tasks without conscious awareness of these previous experiences. Procedural memory guides the processes we perform, and most frequently resides below the level of conscious awareness. When needed, procedural memories are automatically retrieved and utilized for execution of the integrated procedures involved in both cognitive and motor skills, from tying shoes, to reading, to flying an airplane.
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Pergamon-Elsevier Science Ltd2024
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