Explores how inflammation promotes tumor growth and immunosuppression, focusing on the role of inflammatory cells like MDSCs and neutrophils in the tumor microenvironment.
Explores p53's pivotal role in cellular stability, DNA repair, and tumor suppression, emphasizing TP53 mutations and DNA double-strand break repair mechanisms.
Covers the decline of cancer death rates, conventional and targeted anticancer drugs, surgical oncology, radiotherapy, chemotherapy, resistance mechanisms, and the history of targeted drugs and EGFR targeting.
Explores the complexity and fundamental capabilities of cancer, focusing on hallmarks like sustained proliferative signaling and evading growth suppressors.