Category
Pharmacokinetics
Related lectures (62)
Pharmacokinetics: Drug Absorption and Distribution
Explores drug absorption, distribution, and clinical implications, focusing on salicylate poisoning and drug trapping in lysosomes.
Pharmacokinetic & Pharmacodynamic Evaluations
Covers the principles of pharmacokinetics and pharmacodynamics, including drug exposure-response relationships.
Pharmacokinetic & Pharmacodynamic Studies
Discusses the importance of assessing PK/PD relationships in drug development and the use of multiple PD biomarkers.
Interrogating Drugs' Mode of Action
Delves into enzyme inhibition, reversible and irreversible binding, and covalent drugs, exploring drug modes of action and their impact on drug efficacy.
Drug Targets: Adrenergic Signaling
Explores drug targets and adrenergic signaling, covering receptors, enzymes, and transporter proteins.
Preclinical Animal Models: Selection & Rationale
Explores the selection and rationale of preclinical animal models in drug development, emphasizing the 10 to 15-year path to a marketed small-molecule drug.
Pharmacokinetics Modeling: Zero and First-Order Kinetics
Explores pharmacokinetics modeling, covering zero and first-order kinetics, drug distribution, and key parameters for drug elimination.
Identifying Correct Target in Medical Chemistry
Explores target identification, efficacy, and safety in medical chemistry, emphasizing the importance of on-target specificity and drug design.
Pharmacological Targets and Interventions
Explores targets for drug action and the design of specific inhibitors.
Drug Targets: ligand-gated ion channels and kinase-linked receptors
Explores drug targets in ligand-gated ion channels and kinase-linked receptors, focusing on GABAA receptors, benzodiazepines, and insulin therapy.