Johan AuwerxJohan Auwerx is Professor at the École Polytechnique Fédérale in Lausanne, Switzerland, where he occupies the Nestle Chair in Energy Metabolism. Dr. Auwerx has been using molecular physiology and systems genetics to understand metabolism in health, aging and disease. Much of his work focused on understanding how diet, exercise and hormones control metabolism through changing the expression of genes by altering the activity of transcription factors and their associated cofactors. His work was instrumental for the development of agonists of nuclear receptors - a particular class of transcription factors - into drugs, which now are used to treat high blood lipid levels, fatty liver, and type 2 diabetes. Dr. Auwerx was amongst the first to recognize that transcriptional cofactors, which fine-tune the activity of transcription factors, act as energy sensors/effectors that influence metabolic homeostasis. His research validated these cofactors as novel targets to treat metabolic diseases, and spurred the clinical use of natural compounds, such as resveratrol, as modulators of these cofactor pathways.
Johan Auwerx was elected as a member of EMBO in 2003 and is the recipient of a dozen of international scientific prizes, including the Danone International Nutrition Award, the Oskar Minkowski Prize, and the Morgagni Gold Medal. His work is highly cited by his peers with a h-factor of over 100. He is an editorial board member of several journals, including Cell Metabolism, Molecular Systems Biology, The EMBO Journal, Journal of Cell Biology, Cell, and Science. Dr. Auwerx co-founded a handful of biotech companies, including Carex, PhytoDia, and most recently Mitobridge, and has served on several scientific advisory boards.
Dr. Auwerx received both his MD and PhD in Molecular Endocrinology at the Katholieke Universiteit in Leuven, Belgium. He was a post-doctoral research fellow in the Departments of Medicine and Genetics of the University of Washington in Seattle.
Georges WagnièresGeorges Wagnières received his diploma degree (MSc) in physics from the University of Lausanne, Switzerland, in 1986. He obtained his doctorate in science (PhD) in physics (Biomedical optics) from the Swiss Federal Institute of Technology at Lausanne (EPFL) in 1992 and did a postdoctoral work in the Wellman Laboratories of Photomedicine (Harvard Medical School), Boston, USA, from 1993 to 1994. He also obtained a Master degree in Management of Technology delivered by the Ecole des Hautes Etudes Commerciales (HEC) of Lausanne University and the EPFL in 2001. Georges Wagnières manages a research group active in the fields of: - Detection of early superficial cancers by fluorescence imaging. - Characterization of early superficial cancers by high magnification narrow band imaging. - In vivo and in vitro measurement of the vascular and tissular oxygen concentration by time-resolved luminescence spectroscopy and imaging. - Preclinical and clinical study of new photosensitizers for photodynamic therapy (PDT). - Treatment of neurodegenerative conditions (Alzheimer, Parkinson's diseases) by photobiomodulation. - Preclinical and clinical photodynamic therapy of inflammatory bowel diseases and atheroscerotic plaque. - Improvement of the selective vascular extravasation of chemotherapeutic agents by PDT. - Monitoring the light dosimetry during PDT by fluorescence spectroscopy and imaging. - Monitoring laser treatments of the retina by reflectance imaging. - Light dosimetry and tissue optical spectroscopy. - Radiometry. - Development of light delivery systems for biomedical applications. Georges Wagnières is also co-founder and was chairman of one spin-off companies: - Medlight SA, founded in July 1997, which develops, produces and commercializes light distributors for photodynamic therapy. Georges Wagnières has currently authored more than 235 papers (more than 150 in international journals with review board) and is inventor of 18 patents. He supervised 12 PhD students up to now, and currently teaches biomedical optics and photomedicine in master programs and doctoral schools. In addition, he gives the course entitled "Physique Générale I" to biology first year students registered to the Biology School of the Lausanne's University. MAIN PUBLICATIONS Please visit: https://www.epfl.ch/labs/lifmet/wagnieres/publications/ Hannes BleulerSwiss, Born 19.2.1954
1973-78 ETH Zurich, M.S. in Electrical Engineering
1979-84 Teaching Assistant, Doctorate Student at ETH (Inst. of Mechanics)
1984 Ph.D. thesis in Mechatronics (magnetic bearings, Prof. G. Schweitzer)
1985-87 Research Engineer at Hitachi Ltd, Japan, Mechanical Engineering Research Laboratory;
1987 Invited researcher at the Tokyo Institute of Technology (Precision Mechatronics, Prof. K. Ono)
1988-91 Lecturer and Senior Assistant at ETH ; co-foundation of MECOS-Traxler AG
1991-95 Toshiba Chair of "Intelligent Mechatronics" and then regular Associate Professor at The University of Tokyo (Institute of Industrial Science)
1995-present Full Professor at EPFL Lausanne on microrobotics, biomedical robotics;
2000 Co-founder of xitact SA, Morges (robotic surgery instrumentation & simulators)
2002-2006 President Conference of Professors and Lecturers of EPFL, member of Assemblée de l'Ecole
2006 Chairman of ISMB10 (10th International Symposium on Magnetic Bearings, Martigny, Switzerland)
2006 Nomination as member of the Swiss Academy of Technical Sciences (SATW)
Christos ComninellisChristos Comninellis, of Greek origin, born in 1945, received his Bachelor of Science in chemistry (distinction with honor) in 1970 from the University of Alexandria.
From 1971 to 1975, he worked as a chemist at the Institute of chemical engineering at the EPFL, where he achieved his PhD in technical sciences in 1979 for his research on the electrochemical fluorination of organic compounds in anhydrous hydrogen fluoride.
Appointed professor in 1996, he teaches at the Faculty of Basic Sciences (FSB) of the Swiss Federal Institute of Technology, Lausanne (EPFL)
Applied Chemistry.
Transport Phenomena.
Chemical and Electrochemical Technologies Related to the Environment.
Electrochemical Engineering.
He also holds a teaching position at the Haute Ecole Valaisanne Sion (HEVs).
His research work is focused on environmental electrochemistry, electrocatalysis, fuel cell and electrochemical promotion in catalysis. An applied research for the utilization of electrochemical techniques in industry for the protection of the environment is a constant concern within his activities. As a result, the collaboration with the industry enabled the development of oxidation processes with regeneration of the oxidant using a new type of bipolar electrochemical reactor.
Christos Comninellis has published over 170 scientific papers, directed 17 doctoral theses and holds 14 patents. He has participated in over 130 international symposia, giving five plenary lectures during the last five years. He has been president of the Evaluation Committee of the FSB since the beginning of 2004 and is member of the jury of the EPFL prize for outstanding PhD-thesis.
Horst VogelHorst Vogel est né en 1948 à Würzburg, Allemagne. Après ses études en chimie, il obtient le diplôme de chimie en 1974 de l'Université de Würzburg.Il entreprend ensuite un travail de doctorat au Max-Planck Institut für Biophysikalische Chemie de Göttingen, et obtient en 1978 le grade de docteur ès sciences de l'Université de Göttingen. De 1978 à 1983 il effectue des recherches au Max-Planck Institut für Biologie à Tübingen et en 1984, il rejoint le Biocentre à Bâle où il travaille jusqu'en 1989, effectuant une année au Karolinska Institute à Stockholm. En 1989, Horst Vogel rejoint l'institut de chimie physique de l'EPFL où il dirige un groupe travaillant dans les domaines de la biophysique et de la bioélectronique.
Depuis le 1er octobre 1994 il est profeseur en chimie physique des polymères et membranes au Département de chimie de EPFL. Ses intérêts de recherche sont l'étude de la structure et de la dynamique de récepteurs membranaires et l'auto-assemblage des biomolécules aux interfaces pour développer de nouveaux biocapteurs dans le domaine de micro- et nanotechnologie. Il enseigne les sciences du vivant, la biophysique et biochimie, et des chapitres concernant la biotechnologie.
Dipl. in Chemistry1974-Univ. Würzburg, DE
Ph.D.-1978-MPI für Biophys. Chemie, Göttingen, DE
