In artificial intelligence, an expert system is a computer system emulating the decision-making ability of a human expert. Expert systems are designed to solve complex problems by reasoning through bodies of knowledge, represented mainly as if–then rules rather than through conventional procedural code. The first expert systems were created in the 1970s and then proliferated in the 1980s. Expert systems were among the first truly successful forms of artificial intelligence (AI) software. An expert system is divided into two subsystems: the inference engine and the knowledge base. The knowledge base represents facts and rules. The inference engine applies the rules to the known facts to deduce new facts. Inference engines can also include explanation and debugging abilities. Soon after the dawn of modern computers in the late 1940s and early 1950s, researchers started realizing the immense potential these machines had for modern society. One of the first challenges was to make such machines capable of “thinking” like humans – in particular, making these machines capable of making important decisions the way humans do. The medical/healthcare field presented the tantalizing challenge of enabling these machines to make medical diagnostic decisions. Thus, in the late 1950s, right after the information age had fully arrived, researchers started experimenting with the prospect of using computer technology to emulate human decision making. For example, biomedical researchers started creating computer-aided systems for diagnostic applications in medicine and biology. These early diagnostic systems used patients’ symptoms and laboratory test results as inputs to generate a diagnostic outcome. These systems were often described as the early forms of expert systems. However, researchers realized that there were significant limitations when using traditional methods such as flow charts, statistical pattern matching, or probability theory. This previous situation gradually led to the development of expert systems, which used knowledge-based approaches.

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